CADM2
-
Official Full Name
cell adhesion molecule 2
-
Overview
This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin;(Ig) superfamily. The encoded protein has three Ig-like domains and a cytosolic protein 4.1 binding site near the;C-terminus. Proteins belonging to the protein 4.1 family crosslink spectrin and interact with other cytoskeletal;proteins. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
CADM2; cell adhesion molecule 2; IGSF4D, immunoglobulin superfamily, member 4D; Necl 3; NECL3; nectin like 3; SynCAM2; nectin-like 3; nectin-like protein 3; immunoglobulin superfamily member 4D; immunoglobulin superfamily, member 4D; IGSF4D; Necl-3; synC;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.coli
- HEK293
- Human Cell
- Mammalian Cell
- Mammalian cells
- Fc
- His
- His (Fc)
- Avi
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- CADM2 Related Research Area
CADM2 involved in several pathways and played different roles in them. We selected most pathways CADM2 participated on our site, such as Adherens junctions interactions, Cell junction organization, Cell-Cell communication, which may be useful for your reference. Also, other proteins which involved in the same pathway with CADM2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adherens junctions interactions | CDH12;CADM2A;CDH3;CDH2;CTNNA1;CDH6;CDH24;CDH9;CDH17 |
| Cell junction organization | COL17A1;CLDN23;PARVB;CDH13;PVRL2L;CDH17;CDH5;CDH2;LIMS1 |
| Cell-Cell communication | CDH9;CDH3;DST;KIRRELB;CDH6;RSU1;DSCAM;CADM2A;CLDN7 |
| Cell-cell junction organization | CDH18A;CDH17;CDH18;CLDN3;CDH10;PVRL1A;CDH8;CTNND1;CDH12A |
CADM2 has several biochemical functions, for example, cell adhesion molecule binding, protein homodimerization activity, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CADM2 itself. We selected most functions CADM2 had, and list some proteins which have the same functions with CADM2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cell adhesion molecule binding | NPTN;NRXN2;NRXN3;LILRB2;CD1D;CXADR;MSN;CD226;VCAM1 |
| protein homodimerization activity | SMAD1;PDXK;SLC4A1;PYCARD;IKZF3;DMBX1;LDB1;CRYM;UGT1A7 |
| receptor activity | CD93;ITGB3B;GPA33;CD200;GRIA2B;TLR6;CADM4;MCC;IL18RAP |
| receptor binding | PVRL2L;LAMA4;HTT;IL1RAPL1;TNFSF13B;PEX14;FGF10A;KCNJ10;ADAM10 |
CADM2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CADM2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CADM2.
- Q&As
- Reviews
Q&As (5)
Ask a questionCADM2's role in immune cell adhesion and recognition is relevant to vaccine development and immunotherapy strategies, as it influences immune cell interactions and responses.
CADM2 expression varies during development and contributes to tissue development and cellular differentiation, particularly in the nervous system
CADM2 is essential for neural cell adhesion and synaptic plasticity, contributing to the formation and maintenance of neural connections. Dysregulation of CADM2 has been linked to neurological disorders like schizophrenia and autism spectrum disorders.
CADM2 plays a role in immune cell interactions and modulates immune responses. Its involvement in autoimmune diseases and cancer immunology is an area of ongoing research.
Post-translational modifications, such as phosphorylation and glycosylation, modulate CADM2's interactions and functions, affecting cellular adhesion and signaling pathways.
Customer Reviews (3)
Write a reviewThis is hands down the best product I've ever tried.
It's made a significant difference in my workouts and recovery time.
I've been using the product for a few months now, and it has exceeded my expectations.
Ask a Question for All CADM2 Products
Required fields are marked with *
My Review for All CADM2 Products
Required fields are marked with *
