CADPS2
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Official Full Name
Ca++-dependent secretion activator 2
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Overview
This gene encodes a member of the calcium-dependent activator of secretion (CAPS) protein family, which are calcium binding proteins that regulate the exocytosis of synaptic and dense-core vesicles in neurons and neuroendocrine cells. Mutations in this gene may contribute to autism susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
CADPS2; Ca++-dependent secretion activator 2; Ca++ dependent activator protein for secretion 2; calcium-dependent secretion activator 2; CAPS-2; Ca2+-dependent activator protein for secretion 2; calcium-dependent activator protein for secretion 2; FLJ4085;
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | CADPS2-2293H | Recombinant Human CADPS2 Protein, MYC/DDK-tagged | HEK293 | Myc/DDK | ||
Mouse | Cadps2-1934M | Recombinant Mouse Cadps2 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
CADPS2 involved in several pathways and played different roles in them. We selected most pathways CADPS2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CADPS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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CADPS2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CADPS2 itself. We selected most functions CADPS2 had, and list some proteins which have the same functions with CADPS2. You can find most of the proteins on our site.
Function | Related Protein |
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CADPS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CADPS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CADPS2.
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Q&As (5)
Ask a questionCADPS2 interacts with various presynaptic proteins, including Munc13, RIM, and voltage-gated calcium channels. These interactions are critical for its role in synaptic vesicle exocytosis.
CADPS2 is involved in the replenishment of the readily releasable pool of synaptic vesicles, ensuring efficient neurotransmitter release during sustained neuronal activity.
CADPS2 contributes to the regulation of LTP, a cellular mechanism underlying learning and memory, by modulating neurotransmitter release and synaptic strength.
CADPS2 is distinct from synaptophysin and synaptobrevin because it specifically functions in the regulation of synaptic vesicle exocytosis, whereas synaptophysin and synaptobrevin are involved in vesicle trafficking and fusion.
CADPS2 helps in the priming of synaptic vesicles by binding to calcium ions and facilitating the assembly of the SNARE complex, which is essential for vesicle fusion and neurotransmitter release.
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