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CALML5

  • Official Full Name

    Calmodulin-like 5

  • Overview

    This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes.
  • Synonyms

    CALML5;Calmodulin-like 5;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rhesus Macaque
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • SUMO
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CALML5-0307H Recombinant Human CALML5 Protein, GST-Tagged Wheat Germ GST
Human CALML5-10673H Recombinant Human CALML5, GST-tagged E.coli GST 1-146a.a.
Human CALML5-3928H Recombinant Human CALML5, His & GST tagged E.coli His/GST
Human CALML5-7886HCL Recombinant Human CALML5 293 Cell Lysate HEK293 N/A
Human CALML5-369H Recombinant Human CALML5 Protein, His-tagged E.coli His Me1~Glu146
Human CALML5-3241H Recombinant Human CALML5 protein, His-tagged E.coli His 1-120 aa
Human CALML5-3066HF Recombinant Full Length Human CALML5 Protein, GST-tagged In Vitro Cell Free System GST 146 amino acids
Human CALML5-4984H Recombinant Human CALML5 protein, His-SUMO-tagged E.coli His-SUMO 2-146aa
Human CALML5-0818H Recombinant Human CALML5 Protein (Met1-Glu146), His tagged E.coli His Met1-Glu146
Rhesus Macaque CALML5-609R Recombinant Rhesus monkey CALML5 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CALML5-437R-B Recombinant Rhesus Macaque CALML5 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CALML5-437R Recombinant Rhesus Macaque CALML5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CALML5 involved in several pathways and played different roles in them. We selected most pathways CALML5 participated on our site, such as Ras signaling pathway, Rap signaling pathway, Calcium signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CALML5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ras signaling pathwayRASGRP3;SHC1;RALB;FGF2;STK4;FGF22;RELA;GNB2;VEGFA
Rap signaling pathwayCALM4;PIK3R5;MAGI1;INS2;ITGAL;RAF1;PDGFC;IGF1;MRAS
Calcium signaling pathwayCHRM5;TACR1;ATP2A1;PRKACAA;MYLK;TNNC1;PTAFR;Adcy4;ADRA1D
cGMP-PKG signaling pathwayVASP;ATP2B1;GTF2IRD1;PPP1CA;PIK3CD;BAD;SLC25A5;RGS2;GTF2I
cAMP signaling pathwayPIK3R1;PLCE1;PLD2;PPP1CC;PLN;FFAR2;OXTR;MAPK8;GPR119
Phosphatidylinositol signaling systemPLCB4;IMPAD1;PLCE1;PPIP5K2;CALM2B;PI4KA;INPP5L;IPMK;MTMR7B
Oocyte meiosisMAD2L2;CALML3;CTH1;AURKA;PPP2R5E;YWHAE2;MAD2L1;CDC20;PLCZ1
Adrenergic signaling in cardiomyocytesSCN1B;ADRa1A;AKT3A;SCN1BB;PPP1CB;CAMK2D1;ADCY1B;MAPK14B;TPM2
Vascular smooth muscle contractionCALM4;PRKCB;PRKACAA;PLA2G12A;CALM2A;CALM;GNA13A;NPR1;CACNA1C
Circadian entrainmentCALM3;PRKG2;GRIA1;GNG4;RYR1;PRKCG;KCNJ6;GNGT2;GNB3
Long-term potentiationRPS6KA6;RAP1A;CAMK2A;EP300;CALM2;PRKACG;CAMK2D;ARAF;GRIA2
Neurotrophin signaling pathwayRAC1;PIK3R1;PIK3R3;TP73;MAPK7;CALM2;NRAS;PTPN11;NTF4
Dopaminergic synapsePPP1CB;PLCB1;GNG3;CALM1;GNG5;SLC18A1;DRD2;PRKACA;SLC18A2
Olfactory transductionOR5K1;OR10W1;OLFR688;OLFR1013;OLFR154;OLFR49;OR8A1;OLFR491;OLFR1002
PhototransductionRHO;GNB1;GNAT1;GUCA1A;RCV1;CALM2B;CALM1B;CALML3;CALM1
Inflammatory mediator regulation of TRP channelsIL1R1;PIK3R2;HRH1;HTR2B;ACCN5;CYP4A12A;CYP4A10;CAMK2D;NTRK1
Insulin signaling pathwayFLOT1A;INPPL1;GRB2A;RPS6KB1;MTOR;IRS1;CALM1A;FLOT2A;CALM2
GnRH signaling pathwayMAPK12;MAPK10;PLA2G4C;PLCB3;CACNA1SB;NRAS;CALM3A;GNRHR2;ITPR3
Estrogen signaling pathwayOPRM1;CREB3L3;GNAI3;PRKCD;GNAO1;GNAI2;MMP2;PIK3R5;PRKACA
MelanogenesisFZD2;PRKCG;WNT7A;TCF7;GNA11A;PRKACBA;WNT5A;CREB3L3L;PRKCBA
Oxytocin signaling pathwayCAMK1D;NFATC1;PRKACG;RHOA;RAF1;ROCK2;CACNA2D4;MAP2K1;CAMK1
Renin secretionITPR3;ITPR1;PTGER4;PTGER2;REN;REN2;LOC100328615;PRKACB;PLCB4
Aldosterone synthesis and secretionHSD3B6;ADCY1;Adcy4;CALM1;LDLR;PDE2A;ORAI1;NR4A1;ADCY7
Salivary secretionCALML5;Slc4a2;PLCB2;GNAQ;CALM2;LYZ1;CALM1;ATP1B2;STATH
Gastric acid secretionCAMK2A;ATP4B;SST;CALML5;ATP1A3;PLCB3;SLC26A7;MYLK;GAST
Alzheimers diseaseBAD;NDUFB7;ATP5E;TNFRSF1A;mt-Atp8;NDUFS8;NDUFA13;COX8C;SDHD
AlcoholismGNG8;HIST2H2AA2;CREB3L3;CALM4;HIST1H3C;HIST1H3I;HIST3H3;KRAS;CALM2
PertussisRELA;MAPK9;NOS2;C4BP;C4BPA;C1R;NFKB1;IL1A;TICAM2
Tuberculosiscgr2b;MAPK9;CALM4;HSPD1;RFXANK;EP300;IFNA2;ATP6V0A2;CAMK2B
GliomaCALML5;MAP2K2;MAPK1;PLCG1;ARAF;MAP2K1;SOS1;HRAS;PRKCA

CALML5 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CALML5 itself. We selected most functions CALML5 had, and list some proteins which have the same functions with CALML5. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingTHBS1;PRSS2;PCDH2G17;GUCA1C;PCDH18;SYT3;CAPN3A;Shh;ANXA4

CALML5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CALML5 here. Most of them are supplied by our site. Hope this information will be useful for your research of CALML5.

USP1; YWHAQ; PPP4C; USF2; MAGED1; CD81; K3; Smarcc1; STK4; LRRK2; SLX4; GABARAPL1

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