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CAPN11

Official Full Name

calpain 11
Overview

Calpains constitute a family of intracellular calcium-dependent cysteine proteases. There are eight members in this superfamily. They consist of a variable 80 kDa subunit and an invariant 30 kDa subunit. This calpain protein appears to have protease activity and calcium-binding ability. A similar mouse protein may play a functional role in spermatogenesis and in the regulation of calcium-dependent signal transduction events during meiosis. [provided by RefSeq, Dec 2008]
Synonyms

CAPN11; calpain 11; calpain11; calpain-11; CANP 11; calcium-activated neutral proteinase 11;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Rat

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
His|T7
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CAPN11-290H	Recombinant Human CAPN11 Protein, GST-tagged	Wheat Germ	GST	1 a.a. - 702 a.a.	Inquiry
Human	CAPN11-277HCL	Recombinant Human CAPN11 cell lysate		N/A		Inquiry
Human	CAPN11-1718H	Recombinant Human CAPN11 protein, His & T7-tagged	E.coli	His/T7	Phe539~Gly739 (Accession # Q9UMQ6)	Inquiry
Human	CAPN11-1746HF	Recombinant Full Length Human CAPN11 Protein, GST-tagged	In Vitro Cell Free System	GST	702 amino acids	Inquiry
Rat	CAPN11-1119R	Recombinant Rat CAPN11 Protein	Mammalian Cell	His		Inquiry
Rat	CAPN11-783R	Recombinant Rat CAPN11 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	CAPN11-783R-B	Recombinant Rat CAPN11 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	Capn11-1719R	Recombinant Rat Capn11 protein, His & T7-tagged	E.coli	His/T7	Met1~Leu214 (Accession # Q4V8Q1)	Inquiry

Involved Pathway
Protein Function
Interacting Protein
CAPN11 Related Articles

CAPN11 involved in several pathways and played different roles in them. We selected most pathways CAPN11 participated on our site, such as Integrin-mediated cell adhesion, which may be useful for your reference. Also, other proteins which involved in the same pathway with CAPN11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Integrin-mediated cell adhesion	MAPK4;CAPNS1;CAPN3A;CAPN9;CAPN11;SEPP1A;CAPN5;CAPN10;MYLK2

CAPN11 has several biochemical functions, for example, calcium ion binding, calcium-dependent cysteine-type endopeptidase activity, peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CAPN11 itself. We selected most functions CAPN11 had, and list some proteins which have the same functions with CAPN11. You can find most of the proteins on our site.

Function	Related Protein
calcium ion binding	NOX5;MMP16;PCDH2AB2;NCS1;TPD52;CETN4;ADAM8;ACTN2B;NOTCH1
calcium-dependent cysteine-type endopeptidase activity	PEF1;SRI;CAPN2;CAPN11;CAPN5A;CAPN5;CAPN9;CAPN12;CAPN2B
peptidase activity	UFSP2;GM5077;PSMB9B;CAPN2A;SPG7;TMPRSS4A;MCPT1;C3orf37;CTSB

CAPN11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CAPN11 here. Most of them are supplied by our site. Hope this information will be useful for your research of CAPN11.

PRKAR1A; XRCC6; UNG; ANAPC11

Zhu, DL; Wang, KL; et al. The c-Jun N-terminal Kinases (JNK)/Mitogen-activated Protein Kinase (MAPK) is Responsible for the Protection of Tanshinol (Danshensu) upon H2O2-Induced L-6 Rat Myoblast Cell Injury. ACTA SCIENTIAE VETERINARIAE 42:-(2014).

Zhang, ZQ; Zoltewicz, JS; et al. Human Traumatic Brain Injury Induces Autoantibody Response against Glial Fibrillary Acidic Protein and Its Breakdown Products. PLOS ONE 9:-(2014).