CAPNS1
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Official Full Name
calpain, small subunit 1
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Overview
Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008] -
Synonyms
CAPNS1; calpain, small subunit 1; 30K; CANP; CDPS; CSS1; CANPS; CAPN4; CALPAIN4; calpain small subunit 1; CANP small subunit; calpain regulatory subunit; calpain, small polypeptide; calpain 4, small subunit (30K); calcium-dependent protease, small subunit; calcium-dependent protease small subunit 1; calcium-activated neutral proteinase small subunit;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- C
- Myc
- DDK
- GST
- His
- His (Fc)
- Avi
- His|GST
- SUMO
- Myc|DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- CAPNS1 Related Articles
CAPNS1 involved in several pathways and played different roles in them. We selected most pathways CAPNS1 participated on our site, such as Apoptosis Modulation and Signaling, Degradation of the extracellular matrix, Extracellular matrix organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with CAPNS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Apoptosis Modulation and Signaling | BOK;HN1;HRK;BAG3;BIK;BCL2L10;CDKN2A;PTPN13;BCL2L11 |
Degradation of the extracellular matrix | MMP19;COL23A1;ADAM15;MMP10;BMP1;COL9A1;COL15A1B;MMP8;MMP17 |
Extracellular matrix organization | CEACAM1;BMP1A;COL4A6;CTSD;MMP20;CTSG;JAM2B;CMA1;PCOLCEA |
Integrin-mediated cell adhesion | CAPNS1;SEPP1;CAPN3;CAPN10;SEPP1A;CAPN3A;CAPN9;MAPK4;MYLK2 |
CAPNS1 has several biochemical functions, for example, calcium ion binding, calcium-dependent cysteine-type endopeptidase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CAPNS1 itself. We selected most functions CAPNS1 had, and list some proteins which have the same functions with CAPNS1. You can find most of the proteins on our site.
Function | Related Protein |
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calcium ion binding | DSG1;EFHD1;EGFL6;NOX5;LALBA;RASGRP2;PRRG4;MYLPFA;S100A14 |
calcium-dependent cysteine-type endopeptidase activity | CAPN1A;CAPN2B;CAPN2L;CAPN2A;CAPN1;CAPN3;CAPN5;CAPN1B;GCA |
protein binding | ADAT2;RNF220;DNMT3L;LRRK1;ADAM1B;LAGE3;KCNJ15;WFIKKN1;NKX3-1 |
CAPNS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CAPNS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CAPNS1.
CAPN1; CAPN2; AGTRAP; RASA1; TRAF5; CDK4; ARR3; STAT3; TERF1; ATP5J2; RAB1A
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