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CCKBR

  • Official Full Name

    cholecystokinin B receptor

  • Overview

    This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. [provided by RefSeq, Jul 2008]
  • Synonyms

    CCKBR; cholecystokinin B receptor; GASR; CCK-B; CCK2R; gastrin/cholecystokinin type B receptor; CCK-BR; CCK2-R; CCK2 receptor; CCK-B receptor; gastrin receptor; cholecystokinin-2 receptor;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Bos taurus (Bovine)
  • Canis lupus familiaris (Dog) (Canis familiaris)
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mastomys natalensis (African soft-furred rat) (Praomys natalensis)
  • Mouse
  • Mus musculus (Mouse)
  • Oryctolagus cuniculus (Rabbit)
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • Fc
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CCKBR-24H Recombinant Human CCKBR protein, GST-tagged Wheat Germ GST
Human CCKBR-25H Recombinant Human CCKBR protein Wheat Germ N/A
Human CCKBR-26H Recombinant Human CCKBR protein, GST-tagged Wheat Germ GST
Human CCKBR-168HCL Recombinant Human CCKBR lysate HEK293 N/A
Human CCKBR-1476H Recombinant Human CCKBR protein, Fc-tagged HEK293 Fc Ser22-Phe92
Human CCKBR-589HF Recombinant Full Length Human CCKBR Protein In Vitro Cell Free System 447 amino acids
Mouse CCKBR-2957M Recombinant Mouse CCKBR Protein Mammalian Cell His
Mouse CCKBR-1475M Recombinant Mouse CCKBR protein, Fc-tagged HEK293 Fc Ser22-Phe92
Mouse CCKBR-1390M Recombinant Mouse CCKBR Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CCKBR-1390M-B Recombinant Mouse CCKBR Protein Pre-coupled Magnetic Beads HEK293
Rat CCKBR-1209R Recombinant Rat CCKBR Protein Mammalian Cell His
Rat CCKBR-867R-B Recombinant Rat CCKBR Protein Pre-coupled Magnetic Beads HEK293
Rat CCKBR-867R Recombinant Rat CCKBR Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bos taurus (Bovine) RFL21297BF Recombinant Full Length Bovine Gastrin/Cholecystokinin Type B Receptor(Cckbr) Protein, His-Tagged E.coli expression system His Full Length (1-454)
Canis lupus familiaris (Dog) (Canis familiaris) RFL2944CF Recombinant Full Length Dog Gastrin/Cholecystokinin Type B Receptor(Cckbr) Protein, His-Tagged E.coli expression system His Full Length (1-453)
Homo sapiens (Human) RFL12951HF Recombinant Full Length Human Gastrin/Cholecystokinin Type B Receptor(Cckbr) Protein, His-Tagged E.coli expression system His Full Length (1-447)
Mastomys natalensis (African soft-furred rat) (Praomys natalensis) RFL33926MF Recombinant Full Length Praomys Natalensis Gastrin/Cholecystokinin Type B Receptor(Cckbr) Protein, His-Tagged E.coli expression system His Full Length (1-450)
Mus musculus (Mouse) RFL29424MF Recombinant Full Length Mouse Gastrin/Cholecystokinin Type B Receptor(Cckbr) Protein, His-Tagged E.coli expression system His Full Length (1-453)
Oryctolagus cuniculus (Rabbit) RFL30617OF Recombinant Full Length Rabbit Gastrin/Cholecystokinin Type B Receptor(Cckbr) Protein, His-Tagged E.coli expression system His Full Length (1-452)
Rattus norvegicus (Rat) RFL35140RF Recombinant Full Length Rat Gastrin/Cholecystokinin Type B Receptor(Cckbr) Protein, His-Tagged E.coli expression system His Full Length (1-452)
Chicken CCKBR-1138C Recombinant Chicken CCKBR Mammalian Cell His
Kit-0870 Amine Coupling Kit N/A
Kit-1146 CCKBR CHO-K1 β-Arrestin GPCR Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CCKBR involved in several pathways and played different roles in them. We selected most pathways CCKBR participated on our site, such as Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gastric acid secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCKBR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium signaling pathwayPTGFR;PRKACAA;CACNA1C;PDE1C;MYLK;PLCB2;NOS2A;GRM1;VDAC2
Neuroactive ligand-receptor interactionNPFFR1L3;CALCR;P2RX1;GALR1;GABRA2;GRM2A;APLNRB;LEPR;TAAR10B
Gastric acid secretionSLC9A1;MYLK2;SSTR2;CALML3;CALM3;PLCB3;KCNJ1;SST;PRKACG

CCKBR has several biochemical functions, for example, 1-phosphatidylinositol-3-kinase regulator activity, cholecystokinin receptor activity, gastrin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CCKBR itself. We selected most functions CCKBR had, and list some proteins which have the same functions with CCKBR. You can find most of the proteins on our site.

Function Related Protein
1-phosphatidylinositol-3-kinase regulator activityPIK3R3;PIK3R2;PIK3R6;PIK3R5;PIK3R1;PIK3R3B;CCKBR;PIK3R3A
cholecystokinin receptor activityCCKAR;CCKBR
gastrin receptor activity
phosphatidylinositol phospholipase C activityCCR5;CCR1;PLCH2;CHRM1;CASR;PLCE1;PLCG2;PLCG1;PLCL2
protein bindingMAD2L1BP;LCORL;HM13;RAMP3;SH3YL1;BCL2L14;HILPDA;HMGCR;SNAP91
type B gastrin/cholecystokinin receptor binding

CCKBR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCKBR here. Most of them are supplied by our site. Hope this information will be useful for your research of CCKBR.

PTPN11; NTM; ABL1; FYN; CCK; NCK1; GRB2; PPP1R9B; ATP13A2; Plcg1; Ptpn11

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