CCNC
-
Official Full Name
cyclin C
-
Overview
The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
CCNC; cyclin C; cyclin-C; CycC; CCNC_HUMAN; hSRB11; OTTHUMP00000016897; SRB11 homolog;
- Recombinant Proteins
- Cell & Tissue Lysates
- Chicken
- Human
- Zebrafish
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Sf9 Insect Cell
- Wheat Germ
- GST
- GST|His
- His
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | CDK8/CCNC-256H | Active Recombinant Human CDK8/CCNC, GST&His-tagged | Sf9 Insect Cell | GST/His | ||
Human | CCNC-823H | Recombinant Human CCNC Protein, GST-His-tagged | E.coli | GST/His | ||
Human | CCNC-0657H | Recombinant Human CCNC Protein, GST-Tagged | Wheat Germ | GST | ||
Human | CCNC-07H | Recombinant Human Cyclin C | E.coli | N/A | ||
Human | CCNC-08H | Recombinant Human CCNC, His tagged | E.coli | His | ||
Human | CCNC-27518TH | Recombinant Human CCNC, His-tagged | E.coli | His | ||
Human | CCNC-10859H | Recombinant Human CCNC, His-tagged | E.coli | His | 1-283a.a. | |
Human | CCNC-7714HCL | Recombinant Human CCNC 293 Cell Lysate | HEK293 | N/A | ||
Human | CCNC-7715HCL | Recombinant Human CCNC 293 Cell Lysate | HEK293 | N/A | ||
Human | CCNC-2965HF | Recombinant Full Length Human CCNC Protein, GST-tagged | In Vitro Cell Free System | GST | 283 amino acids | |
Zebrafish | CCNC-10317Z | Recombinant Zebrafish CCNC | Mammalian Cell | His | ||
Chicken | CCNC-4033C | Recombinant Chicken CCNC | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
CCNC involved in several pathways and played different roles in them. We selected most pathways CCNC participated on our site, such as Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants, Constitutive Signaling by NOTCH1 PEST Domain Mutants, Developmental Biology, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCNC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | CDK8;JAG1;HEY2;HEYL;HDAC6;HDAC5;CCNC;ADAM10;HEY1 |
Constitutive Signaling by NOTCH1 PEST Domain Mutants | HDAC5;HDAC6;MIB1;JAG1;CCNC;CDK8;JAG2;HEY1;HEYL |
Developmental Biology | KBTBD7;CLTA;TCF3B;KALRNB;DUSP10;TCF12;MED15;ANK2B;MED6 |
Disease | NUPL2;DERL2;AP1M2;OPN1SW;NMT2;SUPT4H1;VPS37A;MTRR;TIRAP |
Diseases of signal transduction | FGFR1OP2;CTBP1;FGFR1OP;KREMEN1;HEYL;MYO18A;TRIM24;RBP1;KREMEN2 |
Fatty acid, triacylglycerol, and ketone body metabolism | STIL;AGPAT2;CPT1B;MED20;SLC25A20;MED15;ACOT13;SREBF2;MED31 |
Gene Expression | RRN3;ZNF223;TRMT6;CCNT2A;RRP8;ZFP36L1A;PAIP1;C2orf49;ESR2B |
Generic Transcription Pathway | ZFP28;TUBB3;ZNF620;ZNF625;FAM36A;ZNF613;MED6;ZNF483;KRBOX4 |
CCNC has several biochemical functions, for example, cyclin-dependent protein serine/threonine kinase regulator activity, protein binding, ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CCNC itself. We selected most functions CCNC had, and list some proteins which have the same functions with CCNC. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
cyclin-dependent protein serine/threonine kinase regulator activity | CCNL1B;CCNL1;CCNT1;CCNL2;CCNT2A;CCND1;CDK4;CKS2;CCNE1 |
protein binding | PPM1A;CTAG2;DNAJA2;KRTAP9-2;ATP6V1E1;NSMCE1;SEC63;RUFY3;MARCKSL1 |
ubiquitin protein ligase activity | MDM2;UBE2NB;TRIP12;LTN1;ANAPC11;STUB1;SIAH2L;RNF220;PDZD4 |
CCNC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCNC here. Most of them are supplied by our site. Hope this information will be useful for your research of CCNC.
CDK8
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All CCNC Products
Required fields are marked with *
My Review for All CCNC Products
Required fields are marked with *