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CD200

  • Official Full Name

    CD200 antigen

  • Overview

    CD200, known as OX-2, is a type I membrane glycoprotein member of the Ig supergene family. CD200 is expressed on B cells, a subset of T cells, thymocytes, follicular dendritic cells, neurons, keratinocytes, vascular endothelium, and some smooth muscle. Th
  • Synonyms

    CD200; CD200 antigen; OX-2 membrane glycoprotein; MRC OX-2 antigen; antigen identified by monoclonal MRC OX-2; OX2; Mox2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus
  • Rhesus Macaque
  • CHO
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293 cells
  • HEK293F
  • HEK293T
  • Human Cell
  • Human cells
  • Human Cells
  • Human Expi293 cells
  • In Vitro Cell Free System
  • Insect Cell
  • Insect cells
  • Mammalian Cell
  • Mammalian cells
  • NS0
  • Wheat Germ
  • C
  • 6×His
  • His
  • Myc
  • DDK
  • DYKDDDDK
  • Fc
  • Avi
  • Fc|His
  • GST
  • hFc
  • His (Fc)
  • human|IgG1|Fc
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CD200-223H Active Recombinant Human CD200, HIgG1 Fc-tagged, mutant CHO Fc
Human CD200-164H Active Recombinant Human CD200, Fc-tagged CHO Fc
Human CD200-101H Active Recombinant Human CD200, HIgG1 Fc-tagged CHO Fc
Human CD200-051H Active Recombinant Human CD200 protein, His/Avi-tagged, Biotinylated HEK293 cells His/Avi Gln31-Lys232
Human CD200-052H Active Recombinant Human CD200 protein, Fc/Avi-tagged, Biotinylated HEK293 cells Fc/Avi Gln31-Gly232
Human CD200-629H Recombinant Human CD200, Fc-His tagged Human Cell Fc/His
Human CD200-202H Recombinant Human CD200, His-tagged E.coli His 31-232aa
Human CD200-630H Active Recombinant Human CD200 protein, His-tagged HEK293 His Met1-Gly232
Human CD200-165H Recombinant Human CD200 protein, Fc-tagged HEK293 human/IgG1/Fc Gln31-Gly232
Human CD200-0741H Recombinant Human CD200 Protein HEK293 N/A
Human CD200-0742H Recombinant Human CD200 Protein, GST-Tagged Wheat Germ GST
Human CD200-0740H Recombinant Human CD200 Protein Wheat Germ N/A
Human CD200-2707HCL Recombinant Human CD200 cell lysate Human Cell N/A
Human CD200-166H Active Recombinant Human CD200 protein, hFc&Avi-tagged, Biotinylated HEK293 hFc&Avi Met1-Gly232
Human CD200-1334H Recombinant Human CD200 Protein (Gln31-Gly232), N-His tagged E.coli N-His Gln31-Gly232
Human CD200-0744H Recombinant Human CD200 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CD200-0743H Recombinant Human CD200 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CD200-2059H Recombinant Human CD200 protein, His-tagged HEK293 His Gln31-Gly232
Human CD200-293H Recombinant Human CD200 Protein (Gln31-Gly232), C-6×His-tagged HEK293 C-6×His Gln31-Gly232
Human CD200-218H Recombinant Human CD200 Protein, DYKDDDDK-tagged Human Cells DYKDDDDK
Human CD200-219H Recombinant Human CD200 Protein, His-tagged Human cells His Gln31-Gly232
Human CD200-305H Recombinant Human CD200 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human CD200-029HB Recombinant Human CD200 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Ala36-Ser163
Human CD200-134H Recombinant Human CD200 Protein, Fc-tagged HEK293 Fc 278
Human CD200-59H Recombinant Human CD200 Protein, His-tagged HEK293 His
Human CD200-213H Recombinant Human CD200 Protein, His-tagged Human Cells His
Human CD200-029H Recombinant Human CD200 protein, His-Avi-tagged HEK293 His-Avi Ala36-Ser163
Human CD200-212H Recombinant Human CD200 Protein, DYKDDDDK/His-tagged Human Expi293 cells DYKDDDDK/His Gln31-Gly232
Human CD200-3012HF Recombinant Full Length Human CD200 Protein In Vitro Cell Free System 295 amino acids
Human CD200-151H Active Recombinant Human CD200 protein, hFc-tagged HEK293 hFc Met1-Gly232
Human CD200-03H Active Recombinant Human CD200 Chimera Protein NS0
Human CD200-2658H Active Recombinant Human CD200 protein, His-tagged HEK293 His Gln31-Gly232
Human CD200-01H Active Recombinant Human CD200 Protein, His-Tagged Insect Cell His 211aa
Human CD200-4587H Recombinant Human CD200 Protein (Met1-Gly232), C-His tagged Mammalian cells C-His Met1-Gly232
Human CD200-133H Recombinant Human CD200 Protein, His-tagged HEK293 His 278
Mouse CD200-002M Active Recombinant Mouse CD200, MIgG2a Fc-tagged, mutant CHO Fc
Mouse Cd200-001M Active Recombinant Mouse Cd200, MIgG2a Fc-tagged CHO Fc
Mouse Cd200-982M Active Recombinant Mouse Cd200 protein, Fc-tagged Mammalian cells Fc Gln31-Gly 232
Mouse Cd200-2272M Active Recombinant Mouse Cd200 protein(Met1-Gly232), His-tagged HEK293 C-His Met1-Gly232
Mouse CD200-2638MCL Recombinant Mouse CD200 cell lysate Human Cell N/A
Mouse Cd200-9M Recombinant Mouse Cd200 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Cd200-9M-B Recombinant Mouse Cd200 Protein Pre-coupled Magnetic Beads HEK293
Mouse Cd200-658M Recombinant Mouse Cd200 Protein, His-tagged HEK293F N-His Gln31-Gly232
Mouse Cd200-2053M Recombinant Mouse Cd200 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Cd200-027M Active Recombinant Mouse Cd200 Protein, His-tagged Insect cells His
Mouse CD200-3071M Active Recombinant Mouse CD200 protein, Fc-Avi-tagged, Biotinylated HEK293 Fc-Avi Gln 31-Gly 232
Rat Cd200-659R Recombinant Rat Cd200 Protein, His-tagged CHO N-His Gln31-Gly232
Rat Cd200-660R Recombinant Rat Cd200 Protein, His&GST-tagged E.coli N-His&GST Ala47-Ser271
Cynomolgus Monkey CD200-243C Active Recombinant Cynomolgus Monkey CD200 protein, Fc-tagged CHO Fc
Cynomolgus Monkey CD200-8853C Recombinant Cynomolgus CD200, Fc tagged Human Cell N/A
Cynomolgus Monkey CD200-123C Recombinant Cynomolgus CD200, His tagged Human Cell Fc/His
Cynomolgus Monkey CD200-1041CCL Recombinant Cynomolgus CD200 cell lysate Human Cell N/A
Homo sapiens (Human) RFL19163HF Recombinant Full Length Human Ox-2 Membrane Glycoprotein(Cd200) Protein, His-Tagged E.coli expression system His Full Length (31-278)
Mus musculus (Mouse) RFL15946MF Recombinant Full Length Mouse Ox-2 Membrane Glycoprotein(Cd200) Protein, His-Tagged E.coli expression system His Full Length (31-278)
Rattus norvegicus (Rat) RFL6756RF Recombinant Full Length Rat Ox-2 Membrane Glycoprotein(Cd200) Protein, His-Tagged E.coli expression system His Full Length (31-278)
Rhesus CD200-716R Active Recombinant Rhesus CD200 protein, His-tagged HEK293 His Met1-Gly232
Rhesus CD200-711R Active Recombinant Rhesus CD200 protein, hFc-tagged HEK293 hFc Met1-Gly232
Rhesus Macaque CD200-726R Recombinant Rhesus monkey CD200 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CD200-553R Recombinant Rhesus Macaque CD200 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CD200-553R-B Recombinant Rhesus Macaque CD200 Protein Pre-coupled Magnetic Beads HEK293
Chicken CD200-2486C Recombinant Chicken CD200 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CD200 Related Articles
  • CD200 Related Research Area

CD200 involved in several pathways and played different roles in them. We selected most pathways CD200 participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD200 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemLILRA3;TRAT1;B2ML;TRIM50;SIGLEC7;PIK3AP1;CTS7;UBE2L6;BTLA
Immune SystemHERC5;RNF25;PELI3;DEFB1;ARIH1;BTR02;TREML4;MICA;KIF20A
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellCD300E;CD300LD;LAIR1;LILRA3;KIR2DS2;SIGLEC10;TREM1;KLRG1;SIGLEC8

CD200 has several biochemical functions, for example, cell adhesion molecule binding, protein binding, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CD200 itself. We selected most functions CD200 had, and list some proteins which have the same functions with CD200. You can find most of the proteins on our site.

Function Related Protein
cell adhesion molecule bindingJUP;NLGN2;SDCBP;DSP;NRXN1;SELL;CADM2;LILRB2;NRXN2
protein bindingCEP350;KIF9;XRN1;SERPINF1;AUNIP;GTF2A2;CHMP4C;FLOT2;MYO6
protein homodimerization activityTFAP2A;ANXA9;AMICA1;CTSE;KCNK9;UGT1A6B;TIMELESS;DPP4;ABCD3
receptor activityNLGN3A;CADM1B;ANPEP;CNTNAP1;TREM2;MED12;RET;NLGN4B;PLXNA1
receptor bindingMBL2;PLAUR;ABL2;WNT7AA;ADM;FGF10B;EFNA1;LAMA1;LTB

CD200 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD200 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD200.

CD200R1; HUS1

Koba, S; Nagase, K; et al. Merkel Cell Carcinoma With Glandular Differentiation Admixed With Sweat Gland Carcinoma and Spindle Cell Carcinoma: Histogenesis of Merkel Cell Carcinoma From Hair Follicle Stem Cells. AMERICAN JOURNAL OF DERMATOPATHOLOGY 37:E31-E36(2015).
Nicholls, SM; Copland, DA; et al. Local targeting of the CD200-CD200R axis does not promote corneal graft survival. EXPERIMENTAL EYE RESEARCH 130:1-8(2015).
  • Q&As
  • Reviews

Q&As (7)

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How does CD200 contribute to the regulation of bone marrow and hematopoietic stem cell niches? 10/04/2022

CD200 regulates bone marrow and hematopoietic environments, supporting stem cell maintenance and differentiation.

How does CD200 influence tumor immune evasion and the tumor microenvironment in cancer? 07/10/2021

CD200 contributes to immune evasion in cancers, affecting tumor progression and response to immunotherapy.

What role does CD200 play in the suppression of inflammatory responses in autoimmune diseases? 04/06/2021

CD200 plays a role in suppressing inflammatory responses, which is crucial in autoimmune disease management.

What are the effects of CD200 dysregulation on tissue graft rejection and transplant tolerance? 02/09/2019

Dysregulation of CD200 affects tissue graft rejection, influencing transplant tolerance and success.

How do alterations in CD200 expression impact the aging process and age-related immune changes? 09/17/2018

Changes in CD200 expression impact the aging immune system, affecting age-related immune regulation and function.

What is the impact of CD200 expression on neuroinflammatory processes and neurodegenerative diseases? 03/20/2018

CD200 expression influences neuroinflammatory processes, potentially impacting neurodegenerative diseases.

How does CD200 interact with its receptor CD200R, and what are the implications for immune regulation? 03/18/2018

CD200 interacts with CD200R to modulate immune responses, promoting immune tolerance and reducing inflammation.

Customer Reviews (3)

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Reviews
08/01/2022

    Swift protein sequencing, helps identify unknown proteins.

    05/04/2022

      Great protein crystallization services, key for structural biology.

      05/02/2019

        Invaluable protein-protein interaction assays, integral for research.

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