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CD2BP2

Official Full Name

CD2 (cytoplasmic tail) binding protein 2
Overview

This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.
Synonyms

CD2BP2; CD2 (cytoplasmic tail) binding protein 2; CD2 antigen (cytoplasmic tail) binding protein 2; CD2 antigen cytoplasmic tail-binding protein 2; LIN1; PPP1R59; protein phosphatase 1; regulatory subunit 59; Snu40; FWP010; U5 snRNP 52K protein; CD2 cytoplasmic domain-binding protein 2; protein phosphatase 1, regulatory subunit 59; U5-52K;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rhesus Macaque
Zebrafish

Source

HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CD2BP2-0775H	Recombinant Human CD2BP2 Protein, GST-Tagged	Wheat Germ	GST		Inquiry
Human	CD2BP2-175HCL	Recombinant Human CD2BP2 lysate	HEK293	N/A		Inquiry
Human	CD2BP2-3097HF	Recombinant Full Length Human CD2BP2 Protein, GST-tagged	In Vitro Cell Free System	GST	341 amino acids	Inquiry
Mouse	CD2BP2-3070M	Recombinant Mouse CD2BP2 Protein	Mammalian Cell	His		Inquiry
Mouse	CD2BP2-1450M	Recombinant Mouse CD2BP2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	CD2BP2-1450M-B	Recombinant Mouse CD2BP2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	CD2BP2-735R	Recombinant Rhesus monkey CD2BP2 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	CD2BP2-561R	Recombinant Rhesus Macaque CD2BP2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	CD2BP2-561R-B	Recombinant Rhesus Macaque CD2BP2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	CD2BP2-11196Z	Recombinant Zebrafish CD2BP2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

CD2BP2 involved in several pathways and played different roles in them. We selected most pathways CD2BP2 participated on our site, such as Gene Expression, Processing of Capped Intron-Containing Pre-mRNA, mRNA Splicing, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD2BP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Gene Expression	CBX3A;APOBEC1;ZNF710;HNRNPL2;SNRNP35;ZFP36L1;C22orf28;NR2E1;ZNF157
Processing of Capped Intron-Containing Pre-mRNA	TXNL4A;RBM5;PTBP1;U2AF2;HNRNPR;SF3B2;HNRNPUL1;HNRNPH1;SLBP
mRNA Splicing	PTBP1;RBM5;HNRNPF;HNRNPA0B;PRPF8;ZCRB1;PTBP1A;PDCD7;HNRNPA0A
mRNA Splicing - Major Pathway	PRPF8;HNRPL;BCAS2;HNRNPR;SF3B4;HNRNPA0B;HNRNPH2;HNRNPA0;HNRNPA2B1
mRNA processing	MCTS2;HNRNPABA;HNRNPD;PRMT2;RBM39;SUGP1;FAM120B;CLK1;RPL36A-HNRNPH2

CD2BP2 has several biochemical functions, for example, protein binding, ribonucleoprotein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD2BP2 itself. We selected most functions CD2BP2 had, and list some proteins which have the same functions with CD2BP2. You can find most of the proteins on our site.

Function	Related Protein
protein binding	VDAC1;RAB34;NDFIP1;CTSB;OAS2;NARG1;ATF3;GSG1L;PRADC1
ribonucleoprotein complex binding	TIMM50;ITCH;PRMT7;UHMK1;CKAP5;PES1;RNF135;WDR12;RNASEL

CD2BP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD2BP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD2BP2.

CD2; PRPF6