CD55
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Official Full Name
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
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Overview
CD55 is a 60-70 kD glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein also known as decay-accelerating factor (DAF). It is expressed on hematopoietic cells including erythrocytes and many non-hematopoietic cells. CD55 accelerates the di -
Synonyms
CD55; CD55 molecule, decay accelerating factor for complement (Cromer blood group); DAF, decay accelerating factor for complement (CD55, Cromer blood group system); complement decay-accelerating factor; CR; CROM; TC; CD55 antigen; DAF;
- Recombinant Proteins
- Cell & Tissue Lysates
- Human
- Mouse
- Rat
- E. coli
- E.coli
- HEK293
- HEK293F
- Human Cell
- Human Cells
- In Vitro Cell Free System
- Insect Cell
- Mammalian cells
- Wheat Germ
- C
- hFc
- His
- Fc
- GST
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- CD55 Related Articles
- CD55 Related Research Area
CD55 involved in several pathways and played different roles in them. We selected most pathways CD55 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CD55 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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CD55 has several biochemical functions, for example, carbohydrate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD55 itself. We selected most functions CD55 had, and list some proteins which have the same functions with CD55. You can find most of the proteins on our site.
Function | Related Protein |
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carbohydrate binding | Cd209g;LPHN1;LAYN;SI;GALNT7;LGALS2;PKD1;Clec4n;SIGLEC8 |
CD55 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD55 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD55.
ganglioside_gm1; LCK; glyA; q5nfy5_fratt; q5ngt6_fratt; ywqA; q914e0_9ento
- Q&As
- Reviews
Q&As (5)
Ask a questionGenetic variations in CD55 may influence susceptibility to complement-mediated disorders by affecting the protein's ability to regulate complement activation. This can lead to conditions like paroxysmal nocturnal hemoglobinuria (PNH).
CD55 has immunomodulatory functions beyond complement regulation, influencing T cell responses and contributing to the maintenance of immune tolerance.
CD55 protects cells from complement-mediated lysis by preventing the formation of membrane attack complexes. This contributes to immune evasion by pathogens and self-cells alike.
CD55 consists of extracellular domains responsible for interactions with complement proteins, particularly C3b and C4b. These interactions prevent the formation of membrane attack complexes on host cells.
CD55 dysregulation is associated with autoimmune disorders, where it may contribute to immune system overactivity. Additionally, some pathogens exploit CD55 to evade host immune responses.
Customer Reviews (3)
Write a reviewEfficient shipping and exceptional product quality. This company knows how to serve its customers.
Consistency is key in research, and this product delivers that every time.
We've tried various proteins, but this one stands out for its purity and performance.
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