CDA
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Official Full Name
cytidine deaminase
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Overview
This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias. -
Synonyms
CDA; cytidine deaminase; CDD; Cytidine aminohydrolase; EC 3.5.4.5; small cytidine deaminase; cytosine nucleoside deaminase;
- Recombinant Proteins
- Chicken
- Human
- Zebrafish
- E.coli
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- Myc
- Myc|DDK
- T7|His
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | CDA-796H | Recombinant Human Cytidine Deaminase, His-tagged | E.coli | His | ||
| Human | CDA-206H | Recombinant Human CDA protein, T7/His-tagged | E.coli | T7/His |
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| Human | CDA-317HCL | Recombinant Human CDA Over-ex<x>pression Lysate | HEK293T | Myc/DDK |
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| Human | CDA-26955TH | Recombinant Human CDA, His-tagged | E.coli | His | 146 amino acids |
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| Human | CDA-0894H | Recombinant Human CDA Protein, GST-Tagged | Wheat Germ | GST |
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| Human | CDA-598H | Recombinant Human CDA Protein, His-tagged | E.coli | His | Ala2~Gln146 |
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| Human | CDA-9381H | Recombinant Human CDA protein, His&Myc-tagged | E.coli | His&Myc | 1-146aa |
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| Human | CDA-3132H | Recombinant Human CDA protein, His-tagged | E.coli | His | 42-146 aa | |
| Human | CDA-3108HF | Recombinant Full Length Human CDA Protein, GST-tagged | In Vitro Cell Free System | GST | 146 amino acids |
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| Human | CDA-1079H | Recombinant Human CDA Protein (Ala2-Gln146), His tagged | E.coli | His | Ala2-Gln146 |
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| Zebrafish | CDA-11703Z | Recombinant Zebrafish CDA | Mammalian Cell | His |
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| Chicken | CDA-3925C | Recombinant Chicken CDA | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- CDA Related Articles
CDA involved in several pathways and played different roles in them. We selected most pathways CDA participated on our site, such as Pyrimidine metabolism, Drug metabolism - other enzymes, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Pyrimidine metabolism | POLR2G;NME7;POLD2;TK1;POLA2;CANT1;POLR2B;DUT;POLE |
| Drug metabolism - other enzymes | UGT2A3;UCK2;TK1;DPYD;UCKL1;UPP2;CES1D;NAT;UGT1A2 |
| Metabolic pathways | UGT1AB;DAD1;GALNT2;PNLIP;GALNT6;CHPF2;CRLS1;RDH11;H2-KE6 |
CDA has several biochemical functions, for example, cytidine deaminase activity, nucleoside binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDA itself. We selected most functions CDA had, and list some proteins which have the same functions with CDA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytidine deaminase activity | APOBEC2;APOBEC3G;CDA;WBP2NL;APOBEC1;APOBEC3F;APOBEC3H;AICDA |
| nucleoside binding | AASS;PNP;POLA1;ACTN4;CDA |
| protein binding | EP300;WDR11;JAG1;ZNF649;RGS17;VAV3;SAMHD1;UCP3;ZFPM2A |
| protein homodimerization activity | IKBKB;GDF7;DSCAML1;CCDC88A;SLC39A13;ADD2;DCK;S100A11;GAMT |
| zinc ion binding | PCGF5;RUFY1;LHX6;ESR2;ZNF84;PDLIM5A;RFFL;RNF32;SOD3A |
CDA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDA here. Most of them are supplied by our site. Hope this information will be useful for your research of CDA.
SDCBP; ZBTB24; PSMA1; PTGER3; LNX1; PLEKHB2; WDYHV1
- Q&As
- Reviews
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