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CDC7

  • Official Full Name

    cell division cycle 7 homolog

  • Overview

    The initiation of DNA replication in mammalian cells is a highly coordinated process that ensures duplication of the genome only once per cell division cycle. Origins of replication are dispersed throughout the genome, and their activities are regulated v
  • Synonyms

    CDC7; cell division cycle 7 homolog (S. cerevisiae); CDC7 (cell division cycle 7, S. cerevisiae, homolog) like 1 , CDC7 cell division cycle 7 (S. cerevisiae) , CDC7L1, cell division cycle 7 (S. cerevisiae); cell division cycle 7-related protein kinase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • Insect (sf21)
  • Insect Cell
  • Mammalian Cell
  • Sf9 Insect Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CDC7-22H Active Recombinant Human CDC7/DBF4 Protein, GST-tagged Insect Cell GST
Human CDC7-021H Recombinant Human CDC7 Protein, His-tagged E.coli His
Human CDC7-0958H Active Recombinant Human CDC7 Protein, GST-Tagged Insect Cell GST
Human CDC7-11019H Recombinant Human CDC7, His-tagged E.coli His 1-349a.a.
Human CDC7-997H Recombinant Human Cell Division Cycle 7 Homolog (S. cerevisiae), GST-tagged Sf9 Insect Cell GST
Human CDC7-0957H Recombinant Human CDC7 Protein, GST-Tagged Wheat Germ GST
Human CDC7-7646HCL Recombinant Human CDC7 293 Cell Lysate HEK293 N/A
Human CDC7-1187H Recombinant Human CDC7 Protein (Met1-Thr232), N-His tagged E.coli N-His Met1-Thr232
Human CDC7-6958HF Active Recombinant Full Length Human CDC7 Protein, GST-tagged Insect (sf21) GST 1-574
Rhesus Macaque CDC7-770R Recombinant Rhesus monkey CDC7 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CDC7-596R-B Recombinant Rhesus Macaque CDC7 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CDC7-596R Recombinant Rhesus Macaque CDC7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish CDC7-1793Z Recombinant Zebrafish CDC7 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CDC7 Related Articles

CDC7 involved in several pathways and played different roles in them. We selected most pathways CDC7 participated on our site, such as Cell cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDC7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell cycleSMAD3A;SMC4;ODF2;YWHABB;NDEL1B;CENPP;GADD45BB;TP53;UBE2V2

CDC7 has several biochemical functions, for example, ATP binding, kinase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDC7 itself. We selected most functions CDC7 had, and list some proteins which have the same functions with CDC7. You can find most of the proteins on our site.

Function Related Protein
ATP bindingTTLL5;MVD;MAST2;DSTYK;ACTB;NME2A;BMPR1AA;ATP2B1A;AARS2
kinase activityEPHB4A;UCK2A;KALRN;SMOK2B;STK25B;CAMKK1A;EPHA2A;AKT1;MAPK8B
metal ion bindingITGAE;CA15B;PLD6;SUMF1;ZSCAN20;ZFYVE26;OLA1;MGAT4B;ZFP335
protein bindingFXYD7;RASSF5;BID;CYTH3;KLHL38;TLE4;CLPX;RASSF9;FAM125B
protein kinase activityMAPK12A;STK25A;CDKL5;PINK1;CCL5;FASTKD2;AKT3;MKNK2A;CDKL2
protein serine/threonine kinase activitySGK2B;IRAK2;MAPK6;PRKY;SGK2;NEK1;MYO3A;CHEK1;STK35

CDC7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDC7 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDC7.

MCMBP; ORC5; CDK4; MCM3; CDKN1A; CDKN2A; MCM2; MCM10; ORC6; CHAF1A; DBF4; GPT; CDK9; GRHPR

Hou, Y; Wang, HQ; et al. Effects of CDC7 gene silencing and Rituximab on apoptosis in diffuse large B cell lymphoma cells. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 138:2027-2034(2012).
Charych, DH; Coyne, M; et al. Inhibition of Cdc7/Dbf4 kinase activity affects specific phosphorylation sites on MCM2 in cancer cells. JOURNAL OF CELLULAR BIOCHEMISTRY 104:1075-1086(2008).
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