CDIPT
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Official Full Name
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
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Overview
Phosphatidylinositol breakdown products are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. Two enzymes, CDP-diacylglycerol synthase and phosphatidylinositol synthase, are involved in the biosynthesis of phosphatidylinositol. Phosphatidylinositol synthase, a member of the CDP-alcohol phosphatidyl transferase class-I family, is an integral membrane protein found on the cytoplasmic side of the endoplasmic reticulum and the Golgi apparatus. -
Synonyms
CDIPT; CDP-diacylglycerol--inositol 3-phosphatidyltransferase; CDP diacylglycerol inositol 3 phosphatidyltransferase (phosphatidylinositol synthase); phosphatidylinositol synthase; PIS; PIS1; MGC1328; CDP diacylglycerol inositol 3 phosphatidyltransferase (phosphatidylinositol synthase); CDP diacylglycerol inositol 3 phosphatidyltransferase; PtdIns synthase; PI synthase;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- Rhesus Macaque
- Zebrafish
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- CDIPT Related Articles
CDIPT involved in several pathways and played different roles in them. We selected most pathways CDIPT participated on our site, such as 3-phosphoinositide biosynthesis, D-myo-inositol (1,4,5)-trisphosphate biosynthesis, Glycerophospholipid biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDIPT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| 3-phosphoinositide biosynthesis | CDIPT;PIK3R6;PIP5KL1;FIG4 |
| D-myo-inositol (1,4,5)-trisphosphate biosynthesis | PLCD3;CDIPT;PIP5KL1 |
| Glycerophospholipid biosynthesis | AGPAT1;AGPAT2;MGLL;CHAT;PEMT;CHKB;PLD4;CPNE6;STIL |
| Glycerophospholipid metabolism | LPCAT2;PLA2G3;PLD2;PCYT1AA;DGKG;LPIN1;TESCA;GPD1C;LPCAT1 |
| Inositol phosphate metabolism | NUDT11;MTMR6;CDIPT;NUDT10;INPP5KA;MTMR7B;ITPKC;INPPL1;PI4KA |
| Metabolic pathways | MGAT3;ACO2;ASAH1;ATP5J2;GMPPB;NADK;NME1;UGT1A9;NDUFA11 |
| Metabolism | TACO1;SLC5A9;FABP11A;FIG4;CYP11B1;ELOVL1A;NAGS;MED9;SLC5A2 |
| Metabolism of lipids and lipoproteins | COQ7;MED20;DPEP2;SLC27A2;APOBB.1;MED21;INSIG1;MED31;APOA4B.1 |
CDIPT has several biochemical functions, for example, CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity, alcohol binding, carbohydrate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDIPT itself. We selected most functions CDIPT had, and list some proteins which have the same functions with CDIPT. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity | |
| alcohol binding | DPM1;CDIPT |
| carbohydrate binding | GALNT3;GALNT1;NOMO1;Siglece;REG3G;CD302;HBL3;CLEC4A2;CLEC10A |
| diacylglycerol binding | UNC13A;RASGRP4;TRPC2;UNC13B;CDIPT;RASGRP2;RASGRP1;UNC13C;RASGRP3 |
| manganese ion binding | GALNT1;XPNPEP3;GALNT3;IMPA1;MRE11A;PPM1BB;LAP3;HMGCL;PPM1B |
| protein binding | MEIOB;FBLIM1;PLEKHN1;FSHB;GRIK3;KAT2A;PTPN22;AMMECR1;Shh |
CDIPT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDIPT here. Most of them are supplied by our site. Hope this information will be useful for your research of CDIPT.
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