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CDK13

Official Full Name

cyclin-dependent kinase 13
Overview

The protein encoded by this gene is a member of the cyclin-dependent serine/threonine protein kinase family. Members of this family are well known for their essential roles as master switches in cell cycle control. The exact function of this protein has not yet been determined, but it may play a role in mRNA processing and may be involved in regulation of hematopoiesis. Alternatively spliced transcript variants have been described.
Synonyms

CHED; CDC2L; CDC2L5; hCDK13; FLJ35215; KIAA1791; cyclin-dependent kinase 13; OTTHUMP00000159007; OTTHUMP00000159008; CDC2-related protein kinase 5; cell division protein kinase 13; cell division cycle 2-like protein kinase 5; cholinesterase-related cell division controller;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E.coli
HEK293
In Vitro Cell Free System
Insect Cell
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CDK13-02H	Recombinant Human CDK13 protein, GST-tagged	Insect Cell	GST		Inquiry
Human	CDK13-01H	Recombinant Human CDK13/Cyclin K protein, GST-tagged	Insect Cell	GST	CDK13 (516-end) and Cyclin K (Full Length)	Inquiry
Human	CDK13-5137H	Recombinant Human CDK13 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	CDK13-321HCL	Recombinant Human CDK13 cell lysate		N/A		Inquiry
Human	CDK13-3756HF	Recombinant Full Length Human CDK13 Protein, GST-tagged	In Vitro Cell Free System	GST	324 amino acids	Inquiry
Human	CDK13-08H	Recombinant Active Human CDK13/Cyclin K Complex Protein, GST-tagged	Insect Cell	GST		Inquiry
Human	CDK13-724H	Recombinant Human CDK13 Protein, His-tagged	E.coli	N-His	Phe705-Leu998	Inquiry
Mouse	CDK13-3193M	Recombinant Mouse CDK13 Protein	Mammalian Cell	His		Inquiry
Mouse	CDK13-1516M	Recombinant Mouse CDK13 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	CDK13-1516M-B	Recombinant Mouse CDK13 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
CDK13 Related Articles

CDK13 involved in several pathways and played different roles in them. We selected most pathways CDK13 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CDK13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

CDK13 has several biochemical functions, for example, ATP binding, RNA polymerase II carboxy-terminal domain kinase activity, cyclin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDK13 itself. We selected most functions CDK13 had, and list some proteins which have the same functions with CDK13. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	DDX46;ACSL5;HSPA4;PRPF4BA;EPHA6;MAP4K1;GSK3B;ACVR1;ASCC3
RNA polymerase II carboxy-terminal domain kinase activity	CDK9;MAPK1;CDK8;CDK7;CDK13;CDK1;CCNK;CDK12
cyclin binding	PFTK1;FBXW7;CDK14;HDAC3;CDKN1A;CDK2;CDK12;MDFIC;CDK13
cyclin-dependent protein serine/threonine kinase activity	CDK1;CDK10;CDK7;NAT1;PFTK1;CCNK;CDKL5;CDK18;CDK11A
poly(A) RNA binding	RPL3;ZCCHC17;PSIP1;EIF5;ABCF1;CDC5L;EIF2S1B;RSRC2;RBM10
protein binding	UQCRB;ICA1L;ATP2A1;PRRC1;ITM2A;LGI4;C7orf25;ALDOB;CLK2
protein kinase activity	CDK8;TRIM24;ROCK1;ACVR2AA;PRKCHB;RAF1;PRKACAA;PRPF4B;NEK2

CDK13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDK13 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDK13.

CDK4; CDK2; CDC37; PRPF40A; imatinib; npm_alk; Lck; CDK1; EEF2; ARRB2; CCT3

Chu, J; Li, JG; et al. The Influence of 5-Lipoxygenase on Alzheimer's Disease-Related Tau Pathology: In Vivo and In Vitro Evidence. BIOLOGICAL PSYCHIATRY 74:321-328(2013).

Lotan, Y; Bagrodia, A; et al. Prospective Evaluation of a Molecular Marker Panel for Prediction of Recurrence and Cancer-specific Survival After Radical Cystectomy. EUROPEAN UROLOGY 64:465-471(2013).