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CDKL1

Official Full Name

cyclin-dependent kinase-like 1 (CDC2-related kinase)
Overview

This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the nucleus. Alternative splice variants encoding different protein isoforms have been described, but their full-length nature has not been determined.
Synonyms

CDKL1; cyclin-dependent kinase-like 1 (CDC2-related kinase); cyclin-dependent kinase-like 1; KKIALRE; CDC2-related kinase 1; protein kinase p42 KKIALRE; serine/threonine protein kinase KKIALRE; serine/threonine-protein kinase KKIALRE; P42;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Human
Rat
Zebrafish

Source

E.coli
HEK293
Mammalian Cell
Sf21
Sf9 Insect Cell
Wheat Germ

Tag

GST
GST|His
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CDKL1-44H	Active Recombinant Human CDKL1(1-303) Protein, N-His-tagged	Sf21	His	1-303 aa	Inquiry
Human	CDKL1-174H	Recombinant Human CDKL1, GST-tagged	Sf9 Insect Cell	GST		Inquiry
Human	CDKL1-529H	Recombinant Human CDKL1 Protein, GST-His-tagged	E.coli	GST/His		Inquiry
Human	CDKL1-1045H	Recombinant Human CDKL1 Protein, GST-Tagged	Wheat Germ	GST		Inquiry
Human	CDKL1-7619HCL	Recombinant Human CDKL1 293 Cell Lysate	HEK293	N/A		Inquiry
Rat	CDKL1-1310R	Recombinant Rat CDKL1 Protein	Mammalian Cell	His		Inquiry
Rat	CDKL1-968R	Recombinant Rat CDKL1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	CDKL1-968R-B	Recombinant Rat CDKL1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	CDKL1-1107Z	Recombinant Zebrafish CDKL1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

CDKL1 involved in several pathways and played different roles in them. We selected most pathways CDKL1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CDKL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

CDKL1 has several biochemical functions, for example, ATP binding, cyclin-dependent protein serine/threonine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CDKL1 itself. We selected most functions CDKL1 had, and list some proteins which have the same functions with CDKL1. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	CIT;ABCC3;TAP1;CDK11A;VRK2;UBE2B;NLRP14;SPAST;YES1
cyclin-dependent protein serine/threonine kinase activity	CDK5R1;CDK1;CDK20;CDKL4;ICK;PFTK1;CDKL5;CDK14;CDK12

CDKL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDKL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDKL1.

cheA; EDIL3; PSMB5; SIRT1