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CDX1

Official Full Name

caudal type homeobox 1
Overview

This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity.
Synonyms

CDX1; caudal type homeobox 1; caudal type homeo box transcription factor 1; homeobox protein CDX-1; caudal-type homeobox protein 1; caudal-type homeobox protein CDX1; caudal type homeobox transcription factor 1; MGC116915;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse

Source

E. coli
E.coli
HEK293
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A
T7
TEV

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CDX1-1082H	Recombinant Human CDX1 Protein, GST-Tagged	Wheat Germ	GST		Inquiry
Human	CDX1-27916TH	Recombinant Human CDX1	Wheat Germ	N/A	90 amino acids	Inquiry
Human	CDX1-11074H	Recombinant Human CDX1, His-tagged	E.coli	His	C-term-50a.a.	$319 / 25ug
Human	CDX1-7603HCL	Recombinant Human CDX1 293 Cell Lysate	HEK293	N/A		Inquiry
Human	CDX1-488H	Recombinant Human CDX1 Protein, T7-His-TEV-tagged	E. coli	T7-His-TEV		Inquiry
Human	CDX1-3682H	Recombinant Human CDX1 protein, GST-tagged	E.coli	GST	105-154 aa	$319 / 25ug
Mouse	CDX1-3241M	Recombinant Mouse CDX1 Protein	Mammalian Cell	His		Inquiry
Mouse	CDX1-1551M	Recombinant Mouse CDX1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	CDX1-1551M-B	Recombinant Mouse CDX1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Chicken	CDX1-6242C	Recombinant Chicken CDX1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
CDX1 Related Articles

CDX1 involved in several pathways and played different roles in them. We selected most pathways CDX1 participated on our site, such as Regulation of Wnt-mediated beta catenin signaling and target gene transcription, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Regulation of Wnt-mediated beta catenin signaling and target gene transcription	MYOG;ZCCHC12;KRT1;TNIK;AES;SALL4;CYR61;BCL9;HBP1

CDX1 has several biochemical functions, for example, RNA polymerase II distal enhancer sequence-specific DNA binding, protein binding, transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDX1 itself. We selected most functions CDX1 had, and list some proteins which have the same functions with CDX1. You can find most of the proteins on our site.

Function	Related Protein
RNA polymerase II distal enhancer sequence-specific DNA binding	ESRRB;JUN;RXRB;HNRNPC;MEOX2;SFPQ;POU4F1;CDX2;H3F3B
protein binding	SPG11;LRRC26;WIPF1;PPP2R1A;FCGR2B;TACR1;SIAH1;HER5;GLRA1
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding	RELA;HMGA1;SIX3;SIX6;PBX3;CDX1;SPI1;SUB1;HCFC1

CDX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDX1.

CEBPA

Ashley, N; Yeung, TM; et al. Stem Cell Differentiation and Lumen Formation in Colorectal Cancer Cell Lines and Primary Tumors. CANCER RESEARCH 73:5798-5809(2013).

Naran, S; Abrams, P; et al. Bile Salts Differentially Sensitize Esophageal Squamous Cells to CD95 (Fas/Apo-1 Receptor) Mediated Apoptosis. JOURNAL OF SURGICAL RESEARCH 171:504-509(2011).