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CENPF

  • Official Full Name

    centromere protein F, 350/400kDa (mitosin)

  • Overview

    This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease.
  • Synonyms

    CENPF; centromere protein F, 350/400kDa (mitosin); centromere protein F (350/400kD, mitosin); centromere protein F; hcp 1; mitosin; AH antigen; kinetochore protein CENPF; CENP-F kinetochore protein; cell-cycle-dependent 350K nuclear protein; centromere pr;

  • Recombinant Proteins
  • Chicken
  • Human
  • E.coli
  • Insect Cell
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His|Myc
  • MBP
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CENPF-486H Recombinant Human CENPF Protein, His-tagged E.coli His Gln436~Lys637
Human CENPF-1115H Recombinant Human CENPF Protein, GST-Tagged Wheat Germ GST
Human CENPF-2743H Recombinant Human CENPF Protein (1759-2093 aa), His-MBP-tagged Insect Cell His/Myc 1759-2093 aa
Human CENPF-3311H Recombinant Human CENPF protein, His-tagged E.coli His 3011-3210 aa
Human CENPF-2209H Recombinant Human CENPF protein, MBP&His-tagged Insect Cell MBP&His 1759-2093aa
Chicken CENPF-6213C Recombinant Chicken CENPF Mammalian Cell His

CENPF involved in several pathways and played different roles in them. We selected most pathways CENPF participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CENPF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

CENPF has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CENPF itself. We selected most functions CENPF had, and list some proteins which have the same functions with CENPF. You can find most of the proteins on our site.

Function Related Protein

CENPF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CENPF here. Most of them are supplied by our site. Hope this information will be useful for your research of CENPF.

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