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CENPH

  • Official Full Name

    centromere protein H

  • Overview

    Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.
  • Synonyms

    CENPH; centromere protein H; NNF1; MIND kinetochore complex component; homolog (S. cerevisiae); PMF1; CENP H; CENP-H; CENPH_HUMAN; ICEN35; Interphase centromere complex protein 35; Kinetochore protein CENP H; NNF1, MIND kinetochore complex component, homolog; OTTHUMP00000123477; OTTHUMP00000221978; OTTHUMP00000221979; kinetochore protein CENP-H;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Human
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CENPH-1116H Recombinant Human CENPH Protein, GST-Tagged Wheat Germ GST
Human CENPH-3644H Recombinant Human CENPH, His-tagged Human His
Human CENPH-11095H Recombinant Human CENPH, His-tagged E.coli His 1-247a.a.
Human CENPH-26924TH Recombinant Human CENPH, His-tagged E.coli His 112 amino acids
Human CENPH-27395TH Recombinant Human CENPH, His-tagged E.coli His
Human CENPH-325H Recombinant Human CENPH Protein, His-tagged E.coli His Met1~Met247
Human CENPH-7584HCL Recombinant Human CENPH 293 Cell Lysate HEK293 N/A
Human CENPH-3320HF Recombinant Full Length Human CENPH Protein, GST-tagged In Vitro Cell Free System GST 247 amino acids
Human CENPH-745H Recombinant Human CENPH Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CENPH-2687H Recombinant Human CENPH protein, GST-tagged E.coli GST 1-247aa
Mouse CENPH-3285M Recombinant Mouse CENPH Protein Mammalian Cell His
Mouse Cenph-326M Recombinant Mouse Cenph Protein, His-tagged E.coli His Glu28~Leu241
Mouse CENPH-1578M Recombinant Mouse CENPH Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Cenph-2104M Recombinant Mouse Cenph Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse CENPH-1578M-B Recombinant Mouse CENPH Protein Pre-coupled Magnetic Beads HEK293
Zebrafish CENPH-6340Z Recombinant Zebrafish CENPH Mammalian Cell His
Chicken CENPH-6179C Recombinant Chicken CENPH Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CENPH involved in several pathways and played different roles in them. We selected most pathways CENPH participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, Chromosome Maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with CENPH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell CycleCEP152;KNTC1;RAD17;DKC1;CDKN1B;SGOL2;ORC6L;KIF2C;TUBGCP2
Cell Cycle, MitoticPCM1;CEP57;GINS1;CTDNEP1B;MAPRE1A;CENPA;ITGB3BP;PMF1;KIF2A
Chromosome MaintenanceTERF2IP;TINF2;OIP5;WRAP53;CENPQ;ACD;MIS18BP1;NPM1;SMARCA5
Deposition of new CENPA-containing nucleosomes at the centromereCENPH;ITGB3BP;PANE1;CENPL;CENPK;CENPA;RBBP7;CENPO;SMARCA5
M PhaseSETA;NCAPD2;CDCA8;MLF1IP;CENPN;NDEL1;NUDC;GOLGA2;MASTL
Mitotic AnaphaseMIS12;CENPE;MLF1IP;CDCA5;SGOL1;CENPK;NDC80;NDEL1B;RCC2
Mitotic Metaphase and AnaphaseCLIP1;ZWILCH;INCENP;ZWINT;SKA1;PMF1;CENPQ;ITGB3BP;CCDC99
Mitotic PrometaphaseCENPO;ERCC6L;CENPN;NDEL1A;CENPC1;CENPL;ZWILCH;SPC25;SKA2

CENPH has several biochemical functions, for example, kinetochore binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CENPH itself. We selected most functions CENPH had, and list some proteins which have the same functions with CENPH. You can find most of the proteins on our site.

Function Related Protein
kinetochore bindingCENPH;CCDC99;CLASP1A;CLASP1;SPDL1
protein bindingZUFSP;PPP2R5D;PPIF;TSC1;RPSA;MYO18A;PLA2G16;KHDRBS2;RPL37A

CENPH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CENPH here. Most of them are supplied by our site. Hope this information will be useful for your research of CENPH.

MTAP; CENPK; PMVK; EMC1; NDC80; q8xb62_eco57; CENPU; CENPQ; Cenpi; CENPO

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