CENPH
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Official Full Name
centromere protein H
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Overview
Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex. -
Synonyms
CENPH; centromere protein H; NNF1; MIND kinetochore complex component; homolog (S. cerevisiae); PMF1; CENP H; CENP-H; CENPH_HUMAN; ICEN35; Interphase centromere complex protein 35; Kinetochore protein CENP H; NNF1, MIND kinetochore complex component, homolog; OTTHUMP00000123477; OTTHUMP00000221978; OTTHUMP00000221979; kinetochore protein CENP-H;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Human
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | CENPH-1116H | Recombinant Human CENPH Protein, GST-Tagged | Wheat Germ | GST | ||
Human | CENPH-3644H | Recombinant Human CENPH, His-tagged | Human | His | ||
Human | CENPH-11095H | Recombinant Human CENPH, His-tagged | E.coli | His | 1-247a.a. | |
Human | CENPH-26924TH | Recombinant Human CENPH, His-tagged | E.coli | His | 112 amino acids | |
Human | CENPH-27395TH | Recombinant Human CENPH, His-tagged | E.coli | His | ||
Human | CENPH-325H | Recombinant Human CENPH Protein, His-tagged | E.coli | His | Met1~Met247 | |
Human | CENPH-7584HCL | Recombinant Human CENPH 293 Cell Lysate | HEK293 | N/A | ||
Human | CENPH-3320HF | Recombinant Full Length Human CENPH Protein, GST-tagged | In Vitro Cell Free System | GST | 247 amino acids | |
Human | CENPH-745H | Recombinant Human CENPH Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK | ||
Human | CENPH-2687H | Recombinant Human CENPH protein, GST-tagged | E.coli | GST | 1-247aa | |
Mouse | CENPH-3285M | Recombinant Mouse CENPH Protein | Mammalian Cell | His | ||
Mouse | Cenph-326M | Recombinant Mouse Cenph Protein, His-tagged | E.coli | His | Glu28~Leu241 | |
Mouse | CENPH-1578M | Recombinant Mouse CENPH Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | Cenph-2104M | Recombinant Mouse Cenph Protein, Myc/DDK-tagged | HEK293T | Myc/DDK | ||
Mouse | CENPH-1578M-B | Recombinant Mouse CENPH Protein Pre-coupled Magnetic Beads | HEK293 | |||
Zebrafish | CENPH-6340Z | Recombinant Zebrafish CENPH | Mammalian Cell | His | ||
Chicken | CENPH-6179C | Recombinant Chicken CENPH | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
CENPH involved in several pathways and played different roles in them. We selected most pathways CENPH participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, Chromosome Maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with CENPH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Cell Cycle | CEP152;KNTC1;RAD17;DKC1;CDKN1B;SGOL2;ORC6L;KIF2C;TUBGCP2 |
Cell Cycle, Mitotic | PCM1;CEP57;GINS1;CTDNEP1B;MAPRE1A;CENPA;ITGB3BP;PMF1;KIF2A |
Chromosome Maintenance | TERF2IP;TINF2;OIP5;WRAP53;CENPQ;ACD;MIS18BP1;NPM1;SMARCA5 |
Deposition of new CENPA-containing nucleosomes at the centromere | CENPH;ITGB3BP;PANE1;CENPL;CENPK;CENPA;RBBP7;CENPO;SMARCA5 |
M Phase | SETA;NCAPD2;CDCA8;MLF1IP;CENPN;NDEL1;NUDC;GOLGA2;MASTL |
Mitotic Anaphase | MIS12;CENPE;MLF1IP;CDCA5;SGOL1;CENPK;NDC80;NDEL1B;RCC2 |
Mitotic Metaphase and Anaphase | CLIP1;ZWILCH;INCENP;ZWINT;SKA1;PMF1;CENPQ;ITGB3BP;CCDC99 |
Mitotic Prometaphase | CENPO;ERCC6L;CENPN;NDEL1A;CENPC1;CENPL;ZWILCH;SPC25;SKA2 |
CENPH has several biochemical functions, for example, kinetochore binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CENPH itself. We selected most functions CENPH had, and list some proteins which have the same functions with CENPH. You can find most of the proteins on our site.
Function | Related Protein |
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kinetochore binding | CENPH;CCDC99;CLASP1A;CLASP1;SPDL1 |
protein binding | ZUFSP;PPP2R5D;PPIF;TSC1;RPSA;MYO18A;PLA2G16;KHDRBS2;RPL37A |
CENPH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CENPH here. Most of them are supplied by our site. Hope this information will be useful for your research of CENPH.
MTAP; CENPK; PMVK; EMC1; NDC80; q8xb62_eco57; CENPU; CENPQ; Cenpi; CENPO
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