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CHD2

Official Full Name

chromodomain helicase DNA binding protein 2
Overview

The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms

CHD2; chromodomain helicase DNA binding protein 2; EEOC; chromodomain-helicase-DNA-binding protein 2; CHD-2; ATP-dependent helicase CHD2;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CHD2-27813TH	Recombinant Human CHD2	Wheat Germ	N/A	501 amino acids	Inquiry
Human	CHD2-1213H	Recombinant Human CHD2 Protein, GST-Tagged	Wheat Germ	GST		Inquiry
Human	CHD2-24H	Recombinant Human CHD2 protein, GST-tagged	E.coli	GST		Inquiry
Human	CHD2-345HCL	Recombinant Human CHD2 cell lysate		N/A		Inquiry
Human	CHD2-02H	Recombinant Human CHD2 Protein (257-456), N-His tagged	E.coli	N-His	257-456	Inquiry
Human	CHD2-3317HF	Recombinant Full Length Human CHD2 Protein, GST-tagged	In Vitro Cell Free System	GST	501 amino acids	Inquiry
Human	CHD2-74HF	Recombinant Full Length Human CHD2 Protein	In Vitro Cell Free System		501 amino acids	Inquiry
Mouse	CHD2-3378M	Recombinant Mouse CHD2 Protein	Mammalian Cell	His		Inquiry
Mouse	CHD2-1631M	Recombinant Mouse CHD2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	CHD2-1631M-B	Recombinant Mouse CHD2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	CHD2-8331Z	Recombinant Zebrafish CHD2	Mammalian Cell	His		Inquiry
Chicken	CHD2-5407C	Recombinant Chicken CHD2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

CHD2 involved in several pathways and played different roles in them. We selected most pathways CHD2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CHD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

CHD2 has several biochemical functions, for example, ATP binding, ATP-dependent DNA helicase activity, DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHD2 itself. We selected most functions CHD2 had, and list some proteins which have the same functions with CHD2. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	MTHFD1B;NWD1;PAK2A;PINK1;DHX58;SRR;NEK4;UBE2A;ATP6V1AA
ATP-dependent DNA helicase activity	DDX11;DHX9;WRN;G3BP1;XRCC6;CHD2;BRIP1;RTEL1;BLM
DNA binding	HLX1;ZFP39;GTF2F2B;DDB2;FOXF2A;SOX19B;CXXC1A;IFT57;KIF4A
core promoter sequence-specific DNA binding	TRP53;SOX9;NR1D2;NRIP1;MEOX1;REST;ATF4;PROX1;CRY1
histone binding	HIST1H4B;NASP;PRKCBP1L;COPRS;APBB1;TBL1X;CD1d1;ZMYND11;MYSM1
poly(A) RNA binding	PDIA4;MRPL28;FUS;SF3B14;RPL3;DDX39;DDX42;ILF3;MRPL40
protein binding	THSD4;RPL7A;HIP1;FAIM;KLC1;SIRT4;FARS2;TRIM74;RASGRP3

CHD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHD2.

TRIM41; BEND7; TEKT1; THAP1; MID2; SRPK2; PHB; TULP3; SUMO1