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CHD6

Official Full Name

chromodomain helicase DNA binding protein 6
Overview

Chromosomal DNA of eukaryotic cells is compacted by nuclear proteins to form chromatin, an organized nucleoprotein structure that can inhibit gene expression. Several multisubunit protein complexes exist to remodel the chromatin to allow patterns of cell type-specific gene expression. The protein encoded by this gene is thought to be a core member of one or more of these complexes. The encoded protein, which is a member of the SNF2/RAD54 helicase family, contains two chromodomains, a helicase domain, and an ATPase domain.
Synonyms

CHD6; chromodomain helicase DNA binding protein 6; chromodomain-helicase-DNA-binding protein 6; CHD5; dJ620E11.1; FLJ22369; KIAA1335; RIGB; ATP dependent helicase CHD6; ATP-dependent helicase CHD6; CHD-6; CHD6_HUMAN; Radiation induced gene B protein; Radiation-induced gene B protein; RP4-620E11.2; OTTHUMP00000031013; helicase C-terminal domain- and SNF2 N-terminal domain-containing protein;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Mouse	CHD6-3381M	Recombinant Mouse CHD6 Protein	Mammalian Cell	His	Inquiry
Mouse	CHD6-1633M	Recombinant Mouse CHD6 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	CHD6-1633M-B	Recombinant Mouse CHD6 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein
CHD6 Related Articles

CHD6 involved in several pathways and played different roles in them. We selected most pathways CHD6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CHD6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

CHD6 has several biochemical functions, for example, ATP binding, ATP-dependent helicase activity, DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHD6 itself. We selected most functions CHD6 had, and list some proteins which have the same functions with CHD6. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	PRPS2;ABCC1;NTRK3;SNRKA;PCXA;INSRA;TAP2;ROCK2A;TOP2A
ATP-dependent helicase activity	TTF2;DHX36;SNRNP200;CHD4A;BLM;DHX37;RTEL1;CHD6;RECQL5
DNA binding	HIST1H2BL;ZNF563;VDR;ZFP57;ELF2B;ZNF692;DMRTA2;DNAJB6;SSBP3B
DNA-dependent ATPase activity	RAD51L1;RAD51L3;CDK7;XRCC2;SMARCAL1;SMARCA2;MSH6;SMARCA4;IGHMBP2
helicase activity	SNRNP200;MCM3L;RAD54L;DDX19;EIF4A1B;GTF2F2;PEO1;PL10;DHX36
hydrolase activity	PLCH2;TMPRSS4A;HRASLS;Ces2c;PPAPDC3;PLCD1A;DCP1B;FAAH2B;PTPN4A
nucleic acid binding	PRDM8B;QK;SETD1BA;ATF7B;GRSF1;EXOG;GFI1AA;ARIH2;KHDRBS1B
nucleotide binding	RAC3B;ADCY2B;ATP2B3A;ARF3B;FGFR1A;RIPK4;SCAF4;ATP13A;RBM12B1
transcription cofactor binding	KLF4;TRP53;CHD6;FOXO3

CHD6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHD6 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHD6.

Aire

Thomas, RH; Zhang, LM; et al. CHD2 myoclonic encephalopathy is frequently associated with self-induced seizures. NEUROLOGY 84:951-958(2015).

Yamada, M; Sato, N; et al. Association of the Chromodomain Helicase DNA-Binding Protein 4 (CHD4) Missense Variation p.D140E with Cancer: Potential Interaction with Smoking. GENES CHROMOSOMES & CANCER 54:122-128(2015).