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CHD8

  • Official Full Name

    chromodomain helicase DNA binding protein 8

  • Overview

    CHD8 belongs to the chromodomain helicase DNA-binding (CHD) family of ATP-dependent chromatin remodeling proteins. The CHD family of proteins has been shown to play an important role in regulating gene expression by utilizing the energy derived from ATP h
  • Synonyms

    CHD8; chromodomain helicase DNA binding protein 8; helicase with SNF2 domain 1 , HELSNF1; chromodomain-helicase-DNA-binding protein 8; DUPLIN; KIAA1564; axis duplication inhibitor; ATP-dependent helicase CHD8; helicase with SNF2 domain 1; HELSNF1;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CHD8-1217H Recombinant Human CHD8 Protein, GST-Tagged Wheat Germ GST
Human CHD8-773H Recombinant Human CHD8 Protein, His-tagged E.coli N-His Leu823-Arg1288
Mouse CHD8-3383M Recombinant Mouse CHD8 Protein Mammalian Cell His
Mouse CHD8-1635M Recombinant Mouse CHD8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CHD8-1635M-B Recombinant Mouse CHD8 Protein Pre-coupled Magnetic Beads HEK293
Rat CHD8-1366R Recombinant Rat CHD8 Protein Mammalian Cell His
Rat CHD8-1024R Recombinant Rat CHD8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CHD8-1024R-B Recombinant Rat CHD8 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish CHD8-7974Z Recombinant Zebrafish CHD8 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CHD8 involved in several pathways and played different roles in them. We selected most pathways CHD8 participated on our site, such as Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHD8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Wnt signaling pathwayROCK2;PPP3R1B;PRKACA;FBXW2;DKK1B;SOST;PRICKLE2B;FZD8B;WNT5A

CHD8 has several biochemical functions, for example, ATP binding, DNA binding, DNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHD8 itself. We selected most functions CHD8 had, and list some proteins which have the same functions with CHD8. You can find most of the proteins on our site.

Function Related Protein
ATP bindingROS1;GSK3B;ACVR1L;NEK10;EP400;KIF23;NEK9;GRK1B;ATAD5
DNA bindingPRM1;ZFP11;RPL7;FOXP1A;ARID5A;HIST1H2AG;MEF2AA;MCM3AP;ZNF280B
DNA helicase activityCHD8;RECQL;MCM5;MCM3L;SUPV3L1;MCM3;FBXO18;ATRX;PIF1
DNA-dependent ATPase activityMSH3;RAD51D;XRCC3;DHX36;CHD8;TTF2;MSH4;RAD51B;DMC1
armadillo repeat domain bindingCALCOCO1;AXIN2;TCF7L2;AXIN1;LEF1;STRN4;CNOT1;STRN;CTNNBIP1
beta-catenin bindingSLC9A3R2;PSEN1;GRIP1;C;DACT3;SLC9A3R1;LZTS2A;TCF7;DVL3
chromatin bindingPOLE;PHF21B;SIN3B;SETD7;PRKCBB;SOD3;SUV39H1;JARID2;NCAPD3
helicase activitySHPRH;SMARCAL1;ZRANB3;SNRNP200;CHD7;EIF4A1B;MCM8;DHX34;DDX11
histone bindingUHRF2;SET;PKN1;HIST1H4L;NPM1;SMARCA4A;WDTC1;DAXX;CD1d1
hydrolase activityDQX1;FAM108A;TIGARB;MMP14A;PPP3CCA;NUDT4A;REXO4;PPP3CCB;FAAH2B
hydrolase activity, acting on acid anhydridesCHD9;SMARCA4A;CHD8
methylated histone bindingCBX7;ING3;CBX5;TDRD3;PHF13;KAT8;L3MBTL2;L3MBTL1;SUZ12
nucleotide bindingEIF4A1B;PRKACBA;HIPK3B;PTBP2A;RMI1;MOCS2;PFKMB;SF3B4;SBK3
p53 bindingRNF20;NUAK1;TP53BP1;TP53;CREBBP;EHMT1;MSX1;RFFL;TRIM24
protein bindingATXN1;SGK3;PLDN;VDAC1;ZBTB16;COG5;Serpina1b;SKP2;C12orf50

CHD8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHD8 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHD8.

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