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CHIT1

  • Official Full Name

    chitinase 1 (chitotriosidase)

  • Overview

    Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.
  • Synonyms

    CHIT1; chitinase 1 (chitotriosidase); chitotriosidase-1; CHI3; CHIT; CHIT1_HUMAN; Chitinase 1; Chitinase-1; Chitotriosidase; EC 3.2.1.14; FLJ00314; MGC125322; Plasma methylumbelliferyl tetra N acetylchitotetraoside hydrolase; OTTHUMP00000039092; OTTHUMP00000217083; OTTHUMP00000217084; OTTHUMP00000217085; plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase; CHITD;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • Flag
  • GST
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CHIT1-27067TH Recombinant Human CHIT1 Wheat Germ N/A 110 amino acids
Human CHIT1-535H Recombinant Human CHIT1 protein, His-tagged HEK293 His Met1-Asn466
Human CHIT1-658H Recombinant Human CHIT1, His tagged Human Cell His
Human CHIT1-11177H Recombinant Human CHIT1, GST-tagged E.coli GST C-term-350a.a.
Human CHIT1-1238H Recombinant Human CHIT1 Protein, GST-Tagged Wheat Germ GST
Human CHIT1-2533HCL Recombinant Human CHIT1 cell lysate Human Cell N/A
Human CHIT1-3200HF Recombinant Full Length Human CHIT1 Protein, GST-tagged In Vitro Cell Free System GST 466 amino acids
Human CHIT1-3741H Recombinant Human CHIT1 protein, His-tagged E.coli His 117-466 aa
Human CHIT1-1672H Recombinant Human CHIT1 protein, His & T7-tagged E.coli His/T7 Ala193~Asn466 (Accession # Q13231)
Human CHIT1-3212H Recombinant Human CHIT1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CHIT1-600H-B Recombinant Human CHIT1 Protein Pre-coupled Magnetic Beads HEK293
Human CHIT1-1899HFL Recombinant Full Length Human CHIT1 Protein, C-Flag-tagged Mammalian cells Flag
Human CHIT1-600H Recombinant Human CHIT1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CHIT1-2701H Recombinant Human CHIT1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CHIT1-1719H Recombinant Human CHIT1 Protein (Ala22-Asn466), C-His tagged Mammalian cells C-His Ala22-Asn466
Human CHIT1-1257H Active Recombinant Human CHIT1 protein, His-tagged HEK293 His Ala22-Asn466
Human CHIT1-787H Recombinant Human CHIT1 Protein HEK293 466
Human CHIT1-1718H Recombinant Human CHIT1 Protein (Ala193-Asn466), N-His tagged E.coli N-His Ala193-Asn466
Mouse Chit1-1673M Recombinant Mouse Chit1 protein, His & T7-tagged E.coli His/T7 Met210~Ser464 (Accession # Q9D7Q1)
Mouse Chit1-2144M Recombinant Mouse Chit1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Kit-1075 Chitotriosidase Activity Assay Kit (Fluorometric) N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CHIT1 Related Research Area

CHIT1 involved in several pathways and played different roles in them. We selected most pathways CHIT1 participated on our site, such as Amino sugar and nucleotide sugar metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHIT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Amino sugar and nucleotide sugar metabolismPGM3;CYB5R1;CYB5R4;GNPNAT1;MPI;NAGK;CYB5RL;GNPDA1;nanA

CHIT1 has several biochemical functions, for example, chitin binding, chitinase activity, endochitinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHIT1 itself. We selected most functions CHIT1 had, and list some proteins which have the same functions with CHIT1. You can find most of the proteins on our site.

Function Related Protein
chitin bindingCHIA.4;CHIA.2;OVGP1;CHI3L1;CHID1;CTBS;CHIA.1;CHIA.3;CHIT1
chitinase activityCTBS;CHID1;CHIA.2;CHIA.4;CHIA.1;CHIA;CHIA.3;CHIT1;OVGP1
endochitinase activity

CHIT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHIT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHIT1.

  • Q&As
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