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CHML

Official Full Name

choroideremia-like (Rab escort protein 2)
Overview

The product of the CHML gene supports geranylgeranylation of most Rab proteins and may substitute for REP-1 in tissues other than retina. CHML is localized close to the gene for Usher syndrome type II.
Synonyms

CHML; choroideremia-like (Rab escort protein 2); rab proteins geranylgeranyltransferase component A 2; REP 2; CHM like; Choroideraemia like protein; Rab escort protein 2; REP2; OTTHUMP00000037644; REP-2, Rab escort protein 2; choroideraemia-like protein;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

HEK293
In Vitro Cell Free System
Mammalian Cell
S.cerevisiae
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CHML-1141H	Active Recombinant Human Choroideremia-like (Rab Escort Protein 2), His-tagged	S.cerevisiae	His		Inquiry
Human	CHML-1245H	Recombinant Human CHML Protein, GST-Tagged	Wheat Germ	GST		Inquiry
Human	CHML-26718TH	Recombinant Human CHML, His-tagged		His		Inquiry
Human	CHML-350HCL	Recombinant Human CHML cell lysate		N/A		Inquiry
Human	CHML-3203HF	Recombinant Full Length Human CHML Protein, GST-tagged	In Vitro Cell Free System	GST	656 amino acids	Inquiry
Mouse	CHML-3402M	Recombinant Mouse CHML Protein	Mammalian Cell	His		Inquiry
Mouse	CHML-1647M	Recombinant Mouse CHML Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	CHML-1647M-B	Recombinant Mouse CHML Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
CHML Related Articles

CHML involved in several pathways and played different roles in them. We selected most pathways CHML participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CHML were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

CHML has several biochemical functions, for example, GTPase activator activity, Rab GTPase binding, oxidoreductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHML itself. We selected most functions CHML had, and list some proteins which have the same functions with CHML. You can find most of the proteins on our site.

Function	Related Protein
GTPase activator activity	RASGRP3;CDC42EP5;TBC1D2;RIN1;GDI1;RGS13;DEPDC1B;ACAP2;TBC1D5
Rab GTPase binding	ACAP2;RAB11FIP4;ANXA2;HACE1;KIF16B;SYTL4;NDRG1;MYO5B;ZFYVE20
oxidoreductase activity	CYP3A41A;KDM1A;ALDH3A2A;FRRS1;GPX1A;AKR1C21;SPRA;PPM1NA;DEGS1

CHML has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHML here. Most of them are supplied by our site. Hope this information will be useful for your research of CHML.

rpoB

Namiki, Y; Endoh, D; et al. Genetic mutation associated with meiotic metaphase-specific apoptosis in MRL/MpJ mice. MOLECULAR REPRODUCTION AND DEVELOPMENT 64:179-188(2003).

Halford, S; Freedman, MS; et al. Characterization of a novel human opsin gene with wide tissue expression and identification of embedded and flanking genes on chromosome 1q43. GENOMICS 72:203-208(2001).