CHMP5
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Official Full Name
charged multivesicular body protein 5
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Overview
CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 -
Synonyms
CHMP5; charged multivesicular body protein 5; C9orf83, chromatin modifying protein 5 , chromosome 9 open reading frame 83 , SNF7DC2; CGI 34; HSPC177; Vps60; C9orf83; CHMP 5; Chromatin modifying protein 5; Chromosome 9 open reading frame 83; HGNC:26942; hVps60; PNAS 2; SNF7 domain containing protein 2; SNF7DC2; Vacuolar protein sorting 60; SNF7 domain containing 2; chromatin-modifying protein 5; SNF7 domain-containing protein 2; apoptosis-related protein PNAS-2; vacuolar protein sorting-associated protein 60; CGI-34; PNAS-2;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Rhesus Macaque
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- SUMO
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
CHMP5 involved in several pathways and played different roles in them. We selected most pathways CHMP5 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHMP5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Endocytosis | ARFGAP2;ARPC5LB;EPN2;CHMP2BA;RAB11AL;PIP5K1A;GRK1B;TSG101;CHMP6 |
CHMP5 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHMP5 itself. We selected most functions CHMP5 had, and list some proteins which have the same functions with CHMP5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | BMPR1A;IFI30;BTK;NCAPH;ADARB1;DUSP12;CASC3;C14orf166;HOXB7 |
CHMP5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHMP5 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHMP5.
STAMBP; VPS4B; MITD1; USP8; USP54; CAMK2A; APPBP2; pi3p; AURKA; ATP6V1A; BAG6; Vps4b; HNRNPD; Tsg101; Ptpn23
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