CHP
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Official Full Name
chemotaxis-inhibiting protein CHIPS
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Overview
This gene encodes a phosphoprotein that binds to the Na+/H+ exchanger NHE1. This protein serves as an essential cofactor which supports the physiological activity of NHE family members and may play a role in the mitogenic regulation of NHE1. The protein -
Synonyms
chp; chemotaxis-inhibiting protein CHIPS; Chemotaxis inhibiting protein; secreted protein that specifically inhibits the activation of neutrophils and monocytes by binding to the formylated peptide receptor and the C5a receptor; blocks neutrophil migration towards the infection site and hinders the establishment of the initial;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Rat
- Staphylococcus aureus
- Staphylococcus Aureus
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- Yeast
- GST
- His
- His (Fc)
- Avi
- Myc
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | CHP-11197H | Recombinant Human CHP, GST-tagged | E.coli | GST | 1-66a.a. | |
| Human | CHP-1261H | Recombinant Human CHP Protein, GST-Tagged | Wheat Germ | GST |
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| Human | CHP-2583H | Recombinant Human Lcium Binding Protein P22, His-tagged | E.coli | His |
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| Human | CHP-7527HCL | Recombinant Human CHP 293 Cell Lysate | HEK293 | N/A |
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| Human | CHP-3214HF | Recombinant Full Length Human CHP Protein, GST-tagged | In Vitro Cell Free System | GST | 66 amino acids |
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| Rat | CHP-1381R | Recombinant Rat CHP Protein | Mammalian Cell | His |
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| Rat | CHP-1039R-B | Recombinant Rat CHP Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | CHP-1039R | Recombinant Rat CHP Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Staphylococcus aureus | chp-1111S | Recombinant Staphylococcus aureus chp protein, His&Myc-tagged | E.coli | His&Myc | 29-149aa |
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| Staphylococcus Aureus | CHP-2168S | Recombinant Staphylococcus Aureus CHP Protein (29-149 aa), His-tagged | Yeast | His | 29-149 aa |
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- Involved Pathway
- Protein Function
- Interacting Protein
- CHP Related Articles
CHP involved in several pathways and played different roles in them. We selected most pathways CHP participated on our site, such as Alzheimers Disease, Calcium signaling in the CD4+ TCR pathway, Glycosaminoglycan metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Alzheimers Disease | CDK5R1;GRIN1;COX5B;COX6B1;UQCRFS1;PPP3R2;UQCR10;NDUFA3;ATP5G1 |
| Calcium signaling in the CD4+ TCR pathway | RCAN1;AKAP5;JUNB;FKBP1A;POU2F1;BATF3;RCAN2;CHP;CSF2 |
| Glycosaminoglycan metabolism | DSEL;SLC26A2;HAS3;GPC5A;CSPG5B;SLC35B2;KIAA1199;HPSE;BGNB |
| Hyaluronan metabolism | LYVE1;STAB2;HAS1;HAS3;CHP;KIAA1199 |
| Hyaluronan uptake and degradation | LYVE1;CHP;STAB2 |
| Metabolism | B3GNT1;CERS4A;PTPMT1;CKMT2;COX6C;FAAH2A;DDAH1;MED8;AADAC |
| Metabolism of carbohydrates | GYG1B;NHLRC1;SLC25A1A;TREH;B3GNT2A;HS3ST4;B3GNT1;SLC5A2;KHK |
| Role of Calcineurin-dependent NFAT signaling in lymphocytes | CHP;RCAN2;RCAN1;FKBP8 |
CHP has several biochemical functions, for example, calcium ion binding, calcium-dependent protein binding, kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHP itself. We selected most functions CHP had, and list some proteins which have the same functions with CHP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | DOC2D;PCDH2G3;C2CD4A;S100A5;SVEP1;EYS;PLCB2;NRXN1;PCDHAC2 |
| calcium-dependent protein binding | TNNI3;SEC31A;VPS37C;MYO1D;S100P;TNNC1;MBL2;ANXA11;SNAP25 |
| kinase binding | PFKL;CEBPA;CDC37;PRKCD;HAP1;FAS;TRADD;CDC6;PARK7 |
| microtubule binding | SKA2;KIF26A;SPAST;DPYSL5;SERPINB1A;SKA1;RAB11A;NDEL1B;CLIP1 |
| potassium channel regulator activity | CHP;KCNE1;ABCC9;SGK2A;KCNE3;ARPP19A;KCNE1L;KCNMB2;YWHAE |
| protein binding | THEMIS2;ATG4B;TIMM23;UBQLN2;NPC1;BEND7;C1GALT1C1;B3GAT3;UPK3A |
| protein kinase inhibitor activity | DNAJC3;TSACC;CISHB;JIP1;MBIP;TAOK3;PRKRIP1;TRIB3;SOCS1B |
| transporter activity | ABCC6;AQP9B;FABP1A;SLC22A17;TMEM184BA;SLC5A8L;SYPA;NUTF2;CLVS1 |
CHP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHP here. Most of them are supplied by our site. Hope this information will be useful for your research of CHP.
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