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CHRNB4

  • Official Full Name

    cholinergic receptor, nicotinic, beta 4

  • Overview

    Neuronal acetylcholine receptor subunit beta-4 is a protein that in humans is encoded by the CHRNB4 gene.
  • Synonyms

    neuronal acetylcholine receptor subunit beta-4; CHRNB4; OTTHUMP00000185021; neuronal nicotinic receptor beta 4 subunit; cholinergic receptor, nicotinic, beta polypeptide 4; cholinergic receptor, nicotinic, beta 4; ACHB4_HUMAN; Cholinergic receptor nicotinic beta 4; Cholinergic receptor nicotinic beta polypeptide 4; Nicotinic beta 4 Receptor;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Chicken
  • Gallus gallus (Chicken)
  • Homo sapiens (Human)
  • Human
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CHRNB4-1290H Recombinant Human CHRNB4 Protein, GST-Tagged Wheat Germ GST
Human CHRNB4-7511HCL Recombinant Human CHRNB4 293 Cell Lysate HEK293 N/A
Human CHRNB4-782H Recombinant Human CHRNB4 Protein, His-tagged E.coli N-His Arg22-Thr236
Rat CHRNB4-1399R Recombinant Rat CHRNB4 Protein Mammalian Cell His
Rat CHRNB4-1057R Recombinant Rat CHRNB4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CHRNB4-1057R-B Recombinant Rat CHRNB4 Protein Pre-coupled Magnetic Beads HEK293
Bos taurus (Bovine) RFL6293BF Recombinant Full Length Bovine Neuronal Acetylcholine Receptor Subunit Beta-4(Chrnb4) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (20-496)
Gallus gallus (Chicken) RFL21422GF Recombinant Full Length Chicken Neuronal Acetylcholine Receptor Subunit Beta-4(Chrnb4) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (4-470)
Homo sapiens (Human) RFL30050HF Recombinant Full Length Human Neuronal Acetylcholine Receptor Subunit Beta-4(Chrnb4) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (22-498)
Mus musculus (Mouse) RFL10086MF Recombinant Full Length Mouse Neuronal Acetylcholine Receptor Subunit Beta-4(Chrnb4) Protein, His-Tagged E.coli expression system His Full Length (21-495)
Rattus norvegicus (Rat) RFL6483RF Recombinant Full Length Rat Neuronal Acetylcholine Receptor Subunit Beta-4(Chrnb4) Protein, His-Tagged E.coli expression system His Full Length (21-495)
Chicken CHRNB4-6382C Recombinant Chicken CHRNB4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CHRNB4 Related Articles

CHRNB4 involved in several pathways and played different roles in them. We selected most pathways CHRNB4 participated on our site, such as Acetylcholine Binding And Downstream Events, Activation of Nicotinic Acetylcholine Receptors, Cholinergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHRNB4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Acetylcholine Binding And Downstream EventsCHRNA1;CHRNE;CHRNA7;CHRNB4;CHRNA5;CHRNA3;CHRND;CHRNA2;CHRNA4
Activation of Nicotinic Acetylcholine ReceptorsCHRNE;CHRNB4;CHRND;CHRNA5;CHRNA4;CHRNA2;CHRNA7;CHRNA1;CHRNA3
Cholinergic synapseCHRNA4;CREB5;CREB3L1;GNG5;GNG11;CAMK2A;KCNJ4;CAMK2G;KCNJ14
Highly calcium permeable nicotinic acetylcholine receptorsCHRNA2;CHRNA3;CHRNA1;CHRNA4;CHRNB4;CHRNA5;CHRNB2
Highly calcium permeable postsynaptic nicotinic acetylcholine receptorsCHRNA2;CHRNA7;CHRNA5;CHRNA1;CHRNA3;CHRNB4;CHRNB2;CHRNA4
Highly sodium permeable acetylcholine nicotinic receptorsCHRNB4;CHRNE;CHRNA4;CHRNA3;CHRND;CHRNB2
Neuroactive ligand-receptor interactionGRIA3B;CSH2;NPBWR1;PTGER1C;RXFP1;CHRM5A;AVPR2;PTGER4A;MCHR1
Neuronal SystemSYN2;KCNN1B;CPLX2L;KCNC2;KCNG1;KCNQ3;KCNJ1A.4;CHRNA2;NCALDA

CHRNB4 has several biochemical functions, for example, contributes_to acetylcholine binding, acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHRNB4 itself. We selected most functions CHRNB4 had, and list some proteins which have the same functions with CHRNB4. You can find most of the proteins on our site.

Function Related Protein
contributes_to acetylcholine bindingCHRNA9;CHRNA2;CHRNB1;CHRNA10;CHRNE;CHRNA2A;CHRNB3A;CHRND;CHRNA4B
acetylcholine receptor activityCHRNA6;CHRNA3;ANXA9;CHRNB4;CHRNA2;CHRNB2;CHRNA7;CHRNE;CHRNA4
acetylcholine-activated cation-selective channel activityCHRNA6;CHRNA10A;CHRNA5;CHRNA2;CHRNA3;CHRNA4B;CHRNA1;CHRNA7;CHRNB3B
drug bindingADH1;SETD6;CHRM3;CYP4B1;PDE10A;ATP5O;HMGB2;DAAM2;CYP2C9
ligand-gated ion channel activityCLCA2;CHRNB4;CHRNB1;CLCA5;CHRNA3;TRPA1B;CNGA3;CHRNA5;ANXA6
protein heterodimerization activityKCNN1;HIST1H2BB;KCNB2;IRAK2;RRAGD;NFYBA;H2-Q10;CD3E;VEGFA

CHRNB4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHRNB4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHRNB4.

Gelernter, J; Kranzler, HR; et al. Genome-Wide Association Study of Nicotine Dependence in American Populations: Identification of Novel Risk Loci in Both African-Americans and European-Americans. BIOLOGICAL PSYCHIATRY 77:493-503(2015).
Sieminska, A; Jassem, E; et al. Nicotine dependence in an isolated population of Kashubians from North Poland: a population survey. BMC PUBLIC HEALTH 15:-(2015).
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