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CISD2

Official Full Name

CISD2 CDGSH iron sulfur domain 2 [ Homo sapiens ]
Overview

The protein encoded by this gene is a zinc finger protein that localizes to the endoplasmic reticulum. The encoded protein binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2.
Synonyms

1500009M05Rik; 1500026J14Rik; 1500031D15Rik; AI848398; B630006A20Rik; CDGSH iron sulfur domain 2; CDGSH iron-sulfur domain-containing protein 2; CDGSH type domain 2; CISD2; CISD2_HUMAN; Endoplasmic reticulum intermembrane small protein; ERIS; Miner1; MitoNEET related 1; MitoNEET-related 1 protein; NAF-1; Noxp70; Nutrient deprivation autophagy factor 1; Nutrient-deprivation autophagy factor-1; OTTHUMP00000219576; RGD1566242; WFS2; Zcd2; Zinc finger; Zinc finger, CDGSH type domain 2;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Lithobates catesbeiana (American bullfrog) (Rana catesbeiana)
Mouse
Zebrafish

Source

E.coli
E.coli expression system
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CISD2-11254H	Recombinant Human CISD2, His-tagged	E.coli	His	61-135a.a.	$319 / 25ug
Human	CISD2-1379H	Recombinant Human CISD2 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	CISD2-7489HCL	Recombinant Human CISD2 293 Cell Lysate	HEK293	N/A		Inquiry
Human	CISD2-301649H	Recombinant Human CISD2 protein, GST-tagged	E.coli	GST	Pro61-Val135	Inquiry
Human	CISD2-1855HF	Recombinant Full Length Human CISD2 Protein, GST-tagged	In Vitro Cell Free System	GST	135 amino acids	Inquiry
Mouse	CISD2-3482M	Recombinant Mouse CISD2 Protein	Mammalian Cell	His		Inquiry
Mouse	CISD2-1698M-B	Recombinant Mouse CISD2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	CISD2-1698M	Recombinant Mouse CISD2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Lithobates catesbeiana (American bullfrog) (Rana catesbeiana)	RFL33223LF	Recombinant Full Length Lithobates Catesbeiana Cdgsh Iron-Sulfur Domain-Containing Protein 2(Cisd2) Protein, His-Tagged	E.coli expression system	His	Full Length (1-135)	Inquiry
Zebrafish	CISD2-10698Z	Recombinant Zebrafish CISD2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

CISD2 involved in several pathways and played different roles in them. We selected most pathways CISD2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CISD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

CISD2 has several biochemical functions, for example, 2 iron, 2 sulfur cluster binding, metal ion binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CISD2 itself. We selected most functions CISD2 had, and list some proteins which have the same functions with CISD2. You can find most of the proteins on our site.

Function	Related Protein
2 iron, 2 sulfur cluster binding	FECH;ISCA1;AIFM4;CISD1;CISD2;AIFM3;GLRX5;CISD3;AOX3
metal ion binding	ZFP654;CTDSP2;ZNF548;SMPD4;ZNF561;ZNF41;TDRD1;CXXC1A;ZNF354A
poly(A) RNA binding	VSIG8;SRSF11;LRP1;SART1;SYF2;GPATCH4;SRFBP1;ABT1;HNRNPH1
protein binding	VMP1;ROPN1B;FAM151B;CSK;PARN;KCNN4;UBL4A;KBTBD6;TAF8
protein homodimerization activity	NR0B2;NADK2;UNC13A;RAP1GAP;HARS2;ALDH5A1;NETO2;DHDPSL;PDE2A

CISD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CISD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CISD2.

GH1; IKBKE; pi3p