CLC
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Official Full Name
Charcot-Leyden crystal protein
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Overview
Cardiotrophin-like cytokine (CLC); also known as novel neurotrophin-1/B cell stimulating factor-3 (NNT-1/BSF-3); is a member of the interleukin (IL);-6 family of cytokines.1 CLC is expressed highly in spleen and peripheral leukocytes2 and is a target-deri -
Synonyms
CLC; Charcot-Leyden crystal protein; eosinophil lysophospholipase; galectin 10; LGALS10; LPPL_HUMAN; lysolecithin acylhydrolase; MGC149659; galectin-10; GAL10; Gal-10; LGALS10A;
- Recombinant Proteins
- Cell & Tissue Lysates
- Human
- E.coli
- HEK293
- HEK293T
- Wheat Germ
- GST
- His
- Myc
- DDK
- N/A
- N
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | CLC-984H | Recombinant Human Charcot-Leyden Crystal Protein, His-tagged | E.coli | His |
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| Human | CLC-11272H | Recombinant Human CLC, GST-tagged | E.coli | GST | 1-142a.a. | |
| Human | CLC-1408H | Recombinant Human CLC Protein, GST-tagged | Wheat Germ | GST |
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| Human | CLC-28114TH | Recombinant Human CLC, His-tagged | E.coli | His | 162 amino acids |
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| Human | CLC-7479HCL | Recombinant Human CLC 293 Cell Lysate | HEK293 | N/A |
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| Human | CLC-616H | Recombinant Human CLC Protein, His-tagged | E.coli | His | Ser2~Arg142 |
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| Human | CLC-13H | Recombinant Human CLC Protein (Ser2-Arg142), N-His tagged, Animal-free, Carrier-free | E.coli | N-His | Ser2-Arg142 |
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| Human | CLC-1741H | Recombinant Human CLC Protein (Ser2-Arg142), His tagged | E.coli | His | Ser2-Arg142 |
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| Human | CLC-4142H | Recombinant Human CLC Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK |
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- Involved Pathway
- Protein Function
- Interacting Protein
- CLC Related Articles
CLC involved in several pathways and played different roles in them. We selected most pathways CLC participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CLC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
CLC has several biochemical functions, for example, carbohydrate binding, cysteine-type endopeptidase activity involved in apoptotic process, NOT contributes_to lysophospholipase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLC itself. We selected most functions CLC had, and list some proteins which have the same functions with CLC. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| carbohydrate binding | CNTN2;FCER2;CLEC3A;CD209B;CLEC2D;LGALS4;GRIFIN;PYGB;LAYN |
| cysteine-type endopeptidase activity involved in apoptotic process | Casp3;CLC;CASP8 |
| NOT contributes_to lysophospholipase activity | |
| protein binding | CSTF1;NUBP2;TRIM35;TRAPPC2;RNF13;DUSP21;FUBP3;AIFM1;KLHL20 |
CLC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLC here. Most of them are supplied by our site. Hope this information will be useful for your research of CLC.
- Q&As
- Reviews
Q&As (5)
Ask a questionThere is emerging evidence that CLC proteins may play a role in neurological disorders, making them potential targets for drug development in this field.
CLC proteins are involved in the transport of chloride ions in the kidney, and mutations in CLC genes can lead to renal disorders such as Bartter syndrome.
Modulating the activity of CLC proteins may offer potential therapeutic benefits in the treatment of certain renal disorders by restoring normal chloride ion transport.
There is evidence suggesting that CLC proteins may play a role in pain perception, making them potential targets for the development of novel pain medications.
Several research groups are investigating the potential of targeting CLC proteins for therapeutic intervention in muscle disorders and cystic fibrosis.
Customer Reviews (3)
Write a reviewthe high-quality CLC protein is available in various forms, including recombinant proteins and purified samples, enabling researchers to select the most suitable format for their specific experimental setup.
This enables researchers to confidently incorporate CLC into their studies, knowing that they have access to a reliable and well-characterized protein that will contribute to robust and accurate results.
The knowledgeable and responsive support team is dedicated to resolving issues and providing solutions that are tailored to specific experimental requirements.
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