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CLDN5

  • Official Full Name

    claudin 5

  • Overview

    This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
  • Synonyms

    CLDN5; claudin 5; AWAL, TMVCF, transmembrane protein deleted in velocardiofacial syndrome; claudin-5; BEC1; CPETRL1; TMDVCF; transmembrane protein deleted in VCFS; transmembrane protein deleted in velocardiofacial syndrome; AWAL; TMVCF;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Baculovirus-Insect cells
  • E.coli
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Protein Conjugation
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CLDN5-193H Active Recombinant Human CLDN5 Full Length Transmembrane protein(Nanodisc) HEK293 N/A
Human CLDN5-16H Recombinant Human CLDN5 protein, GST-tagged Wheat Germ GST
Human CLDN5-15H Recombinant Human CLDN5 protein, GST-tagged Wheat Germ GST
Human CLDN5-7461HCL Recombinant Human CLDN5 293 Cell Lysate HEK293 N/A
Human CLDN5-0459H Recombinant Human CLDN5 Protein (Met1-Val218), C-His-tagged Baculovirus-Insect cells C-His Met1-Val218
Human CLDN5-640HF Recombinant Full Length Human CLDN5 Protein, GST-tagged In Vitro Cell Free System GST 218 amino acids
Human CLDN5-2790H Recombinant Human CLDN5 Protein, His-tagged, OVA Conjugated Protein Conjugation N-His Val144-Glu159
Mouse CLDN5-3539M Recombinant Mouse CLDN5 Protein Mammalian Cell His
Mouse Cldn5-2791M Recombinant Mouse Cldn5 Protein, His-tagged, OVA Conjugated Protein Conjugation N-His Arg145-Leu160
Mouse CLDN5-1734M-B Recombinant Mouse CLDN5 Protein Pre-coupled Magnetic Beads HEK293
Mouse Cldn5-795M Recombinant Mouse Cldn5 Protein, His-tagged E.coli N-His Met1-Glu7+Met29-Arg81+Gln103-Ala123+Arg145-Leu160+Cys182-Val218
Mouse CLDN5-1734M Recombinant Mouse CLDN5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CLDN5-1436R Recombinant Rat CLDN5 Protein Mammalian Cell His
Rat CLDN5-1094R-B Recombinant Rat CLDN5 Protein Pre-coupled Magnetic Beads HEK293
Rat CLDN5-1094R Recombinant Rat CLDN5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bos taurus (Bovine) RFL364BF Recombinant Full Length Bovine Claudin-5(Cldn5) Protein, His-Tagged E.coli expression system His Full Length (1-218)
Homo sapiens (Human) RFL24308HF Recombinant Full Length Human Claudin-5(Cldn5) Protein, His-Tagged E.coli expression system His Full Length (1-218)
Mus musculus (Mouse) RFL8771MF Recombinant Full Length Mouse Claudin-5(Cldn5) Protein, His-Tagged E.coli expression system His Full Length (1-218)
Rattus norvegicus (Rat) RFL13261RF Recombinant Full Length Rat Claudin-5(Cldn5) Protein, His-Tagged E.coli expression system His Full Length (1-218)
Chicken CLDN5-5775C Recombinant Chicken CLDN5 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CLDN5 Related Research Area

CLDN5 involved in several pathways and played different roles in them. We selected most pathways CLDN5 participated on our site, such as Cell adhesion molecules (CAMs), Tight junction, Leukocyte transendothelial migration, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLDN5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell adhesion molecules (CAMs)HLA-DRB3;ICOSLG;CD276;NEGR1;MHC1UXA2;CLDNC;NLGN1;CD80;CTLA4
Tight junctionCLDNJ;MYL7;CLDN15A;MYH9;MAGI1B;CLDN14;CASKB;CLDN4;CSNK2A2A
Leukocyte transendothelial migrationITGA4;MMP9;JAM3;ITGAM;CLDN11;NCF1;CTNNA3;VAV2;ACTG1
Hepatitis COAS3;PDPK1;CLDN9;OAS1B;NFKBIA;AKT2;TRAF3;MAPK1;MAPK12

CLDN5 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by CLDN5 itself. We selected most functions CLDN5 had, and list some proteins which have the same functions with CLDN5. You can find most of the proteins on our site.

Function Related Protein
molecular_functionADPRM;HIST1H2BD;CYB5R1;MURCA;SOWAHA;GM14436;TMTC2;TBC1D9;DPH7

CLDN5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLDN5 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLDN5.

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Customer Reviews (3)

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Reviews
10/11/2022

    The CLDN5 protein's robustness and stability have contributed significantly to the success of my experiments, enabling precise and reproducible measurements.

    06/23/2018

      Its exceptional performance, in combination with its clear and distinct protein bands, make it an absolute must-have for researchers looking to achieve accurate and reliable results in their experiments.

      10/28/2017

        I highly recommend the CLDN5 protein for a wide range of research applications.

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