CLIC3
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Official Full Name
chloride intracellular channel 3
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Overview
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family. -
Synonyms
CLIC3; chloride intracellular channel 3; chloride intracellular channel protein 3;
- Recombinant Proteins
- Cell & Tissue Lysates
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- In Vitro Cell Free System
- Wheat Germ
- C
- His
- GST
- Myc
- DDK
- Myc|DDK
- N/A
- T7
- Involved Pathway
- Protein Function
- Interacting Protein
CLIC3 involved in several pathways and played different roles in them. We selected most pathways CLIC3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CLIC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
CLIC3 has several biochemical functions, for example, chloride channel activity, NOT glutathione transferase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CLIC3 itself. We selected most functions CLIC3 had, and list some proteins which have the same functions with CLIC3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chloride channel activity | CLCC1;SLC26A11;SLC26A6;FXYD1;SLC26A7;GABRA1;GABRR3;CLICA;CLCN1 |
| NOT glutathione transferase activity | CLIC1;CLIC2;CLIC5;CLIC3;ALOX5AP |
| protein binding | SRSF7;CALCRL;SIX3;IRS2;STAP1;SYNCRIP;S1PR3;C4BPB;PYY |
| voltage-gated ion channel activity | KCNJ1B;CACNG2A;SCN8AB;CLIC1;CLIC5A;CACNA1BA;KCNC2;CLIC2;CACNG2B |
CLIC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLIC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLIC3.
EFHC2; POT1
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