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CLINT1

  • Official Full Name

    clathrin interactor 1

  • Overview

    This gene encodes a protein with similarity to the epsin family of endocytic adapter proteins. The encoded protein interacts with clathrin, the adapter protein AP-1 and phosphoinositides. This protein may be involved in the formation of clathrin coated vesicles and trafficking between the trans-Golgi network and endosomes. Mutations in this gene are associated with a susceptibility to schizophrenia and psychotic disorders. Alternate splicing results in multiple transcript variants.
  • Synonyms

    CLINT1; clathrin interactor 1; CLINT; ENTH; EPNR; KIAA0171; epsinR; epsin 4; enthoprotin; epsin-related protein; clathrin interacting protein localized in the trans-Golgi region; EPN4; FLJ46753;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Chicken
  • Human
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • Yeast
  • GST
  • His
  • SUMO
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CLINT1-1485H Recombinant Human CLINT1 Protein, GST-tagged Wheat Germ GST
Human CLINT1-7444HCL Recombinant Human CLINT1 293 Cell Lysate HEK293 N/A
Human CLINT1-2701H Recombinant Human CLINT1 protein, His-tagged E.coli His 1-625aa
Human CLINT1-3257H Recombinant Human CLINT1 Protein, His-tagged E.coli His
Human CLINT1-2702H Recombinant Human CLINT1 protein, His-SUMO-tagged E.coli His-SUMO 1-625aa
Human CLINT1-2187HF Recombinant Full Length Human CLINT1 Protein, GST-tagged In Vitro Cell Free System GST 625 amino acids
Human CLINT1-2021H Recombinant Human CLINT1 Protein (1-625 aa), His-tagged Yeast His 1-625 aa
Chicken CLINT1-2324C Recombinant Chicken CLINT1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CLINT1 Related Articles

CLINT1 involved in several pathways and played different roles in them. We selected most pathways CLINT1 participated on our site, such as Clathrin derived vesicle budding, Golgi Associated Vesicle Biogenesis, Membrane Trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLINT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Clathrin derived vesicle buddingHIP1R;GAK;PICALMB;BLOC1S1;AP1G1;AP4B1;SNX9A;TPD52L1;SH3D19
Golgi Associated Vesicle BiogenesisAP4B1;AP1B1;HIP1R;CPD;BLOC1S6;NECAP1;TPD52L1;SNX9A;PICALMA
Membrane TraffickingCOPE;DAB2;TFR1B;SCFD1;GORASP1;NAPB;YKT6;SNAPIN;STXBP3
Vesicle-mediated transportHYOU1;MYO6A;MYO6B;TRAPPC2L;SCFD1;NAPB;PLDN;DTNBP1B;ARCN1B
trans-Golgi Network Vesicle BuddingCPD;BLOC1S6;FTH1B;AP3S1;DTNBP1B;HIP1R;PICALM;BLOC1S3;YIPF6

CLINT1 has several biochemical functions, for example, clathrin binding, lipid binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CLINT1 itself. We selected most functions CLINT1 had, and list some proteins which have the same functions with CLINT1. You can find most of the proteins on our site.

Function Related Protein
clathrin bindingRPH3A;SYT1;SYT9B;SYT6;SYT13;SMAP1;SYT4;SYT10;SYT5B
lipid bindingPLEKHA2;FAM125A;LPAR4;Ar;HSP12;STARD13;DBI;BPIFB4;DOK7
protein bindingEPAS1;MLKL;MMP2;NIPSNAP3A;CHCHD3;SUFU;BNIP3;MSH4;TUBG1

CLINT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLINT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLINT1.

Ap1g1; MAP1LC3B; GABARAPL1; MAP1LC3A; GABARAP; GABARAPL2; MAP1LC3C

Jing, WH; Song, YL; et al. Identification of cytochrome P450 isoenzymes involved in metabolism of (+)-praeruptorin A, a calcium channel blocker, by human liver microsomes using ultra high-performance liquid chromatography coupled with tandem mass spectrometry. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 77:175-188(2013).
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