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CMBL

  • Official Full Name

    carboxymethylenebutenolidase homolog (Pseudomonas)

  • Overview

    CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010
  • Synonyms

    CMBL; carboxymethylenebutenolidase homolog (Pseudomonas); carboxymethylenebutenolidase like (Pseudomonas); carboxymethylenebutenolidase homolog; FLJ23617; CMBL_HUMAN; carboxymethylenebutenolidase-like (Pseudomonas);

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CMBL-6960H Recombinant Human Carboxymethylenebutenolidase Homolog (Pseudomonas), His-tagged E.coli His 1-245aa
Human CMBL-1534H Recombinant Human CMBL Protein, GST-tagged Wheat Germ GST
Human CMBL-2504H Recombinant Human CMBL protein, His-tagged E.coli His Met1-Met245
Human CMBL-7421HCL Recombinant Human CMBL 293 Cell Lysate HEK293 N/A
Human CMBL-1900HF Recombinant Full Length Human CMBL Protein, GST-tagged In Vitro Cell Free System GST 245 amino acids
Human CMBL-1535H Recombinant Human CMBL protein, GST-tagged E. coli GST 1-245 aa
Human CMBL-4919H Recombinant Human CMBL Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse CMBL-3622M Recombinant Mouse CMBL Protein Mammalian Cell His
Mouse CMBL-1780M Recombinant Mouse CMBL Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Cmbl-2205M Recombinant Mouse Cmbl Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse CMBL-1780M-B Recombinant Mouse CMBL Protein Pre-coupled Magnetic Beads HEK293
Rat CMBL-1478R Recombinant Rat CMBL Protein Mammalian Cell His
Rat CMBL-1136R-B Recombinant Rat CMBL Protein Pre-coupled Magnetic Beads HEK293
Rat CMBL-1136R Recombinant Rat CMBL Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CMBL-927R Recombinant Rhesus monkey CMBL Protein, His-tagged Mammalian Cell His
Rhesus Macaque CMBL-752R Recombinant Rhesus Macaque CMBL Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CMBL-752R-B Recombinant Rhesus Macaque CMBL Protein Pre-coupled Magnetic Beads HEK293
Zebrafish CMBL-6072Z Recombinant Zebrafish CMBL Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CMBL involved in several pathways and played different roles in them. We selected most pathways CMBL participated on our site, such as Biosynthesis of antibiotics, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with CMBL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Biosynthesis of antibioticsCYP51A1;ADH5;DLST;SDSL;DAO;CMBL;AKR1A1;ACAA2;CTH
Metabolic pathwaysHSD17B1;CYP19A1;PLA2G3;CYP8B1;PGAM2;CYP3A25;DPYD;ALDH2;ALDOCB

CMBL has several biochemical functions, for example, hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CMBL itself. We selected most functions CMBL had, and list some proteins which have the same functions with CMBL. You can find most of the proteins on our site.

Function Related Protein
hydrolase activityPRSS44;MMP14A;LYZ2;LCTLB;KLK1B24;USB1;ATP1A1A.3;ATP2B3B;SACM1LA

CMBL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CMBL here. Most of them are supplied by our site. Hope this information will be useful for your research of CMBL.

CD2BP2; ATIC; ARRB1; CUL2; EIF4A2; TRIP6; SMYD2; PUF60; 2_aha_camp; 8-aha-camp; 8-aha-omethyladenosine; SAP30; Chmp6; H2AFX; SNCA; SMS; Crocc; KIF20B

  • Q&As
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