CNOT8
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Official Full Name
CCR4-NOT transcription complex, subunit 8
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Overview
CCR4-NOT transcription complex subunit 8 is a protein that in humans is encoded by the CNOT8 gene. -
Synonyms
CNOT8; CCR4-NOT transcription complex, subunit 8; POP2; CCR4-NOT transcription complex subunit 8; CAF1; CALIF; hCAF1; PGK promoter directed over production; CAF 1; CAF 2; CAF1 like protein; CAF2; CALIFp; CCR4 associated factor 8; CCR4 NOT transcription complex subunit 8; CNOT 8; POP 2; CAF1-like protein; CCR4-associated factor 8;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
- T7|His
- Involved Pathway
- Protein Function
- Interacting Protein
CNOT8 involved in several pathways and played different roles in them. We selected most pathways CNOT8 participated on our site, such as RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CNOT8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA degradation | MPHOSPH6;TTC37;DnaK;PAN2;PABPC1;EXOSC9;BTG4;DCP1A;NUDT16 |
CNOT8 has several biochemical functions, for example, 3-5-exoribonuclease activity, RNA binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CNOT8 itself. We selected most functions CNOT8 had, and list some proteins which have the same functions with CNOT8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 3-5-exoribonuclease activity | CNOT7;ERI2;PNPT1;DIS3L2;TOE1;DIS3;ERI1;ISG20;EXOSC3 |
| RNA binding | KIN;APOBEC1;RBM12B2;CELF3;TRIM32;EXOSC7;RDM1;RTCD1;DAZL |
| metal ion binding | YOD1;ZFP541;PPP1CC;ZFYVE16;GATA5;AGO2;ZNF446;PRDM1;GDPD4 |
| poly(A)-specific ribonuclease activity | TOE1;PARN;PAN2;CNOT7;CNOT6;CNOT8;PDE12;CNOT6L |
| protein binding | MED15;KLK8;SESTD1;IRAK4;SNAI1;PHB2;NIPSNAP3A;RNF34;TCF4 |
| transcription factor activity, sequence-specific DNA binding | RAB11FIP4A;TSC22D2;ZNF167;CITED1;FOXA;TFEB;ZSCAN20;CBFB;KAT7A |
CNOT8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CNOT8 here. Most of them are supplied by our site. Hope this information will be useful for your research of CNOT8.
CNOT1; BTG1; BTG2; CNOT3; CNOT6
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