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COIL

Official Full Name

Coilin
Overview

Coilin is a component of the nuclear Cajar(coiled) bodies (CBs) which are involved in the function or assembly/disassembly of nucleoplasmic snRNPs. Human coilin is a 576-amino acid protein found enriched in CBs, but is also found in large amounts in the nucleoplasm. Coilin is a constitutive phosphoprotein that is hyperphosphorylated during mitosis and it is thought that hyperphosphorylation triggers CB disassembly during cell replication. Self-interaction and localization have been shown to depend on the phosphorylation state of coilin.
Synonyms

COIL; coilin; p80; coilin p80; CLN80; p80-coilin;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Rhesus Macaque
Zebrafish

Source

E. coli
E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

C
His
GST
His (Fc)
Avi
His|T7
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	COIL-26172TH	Recombinant Human COIL	Wheat Germ	N/A	99 amino acids	Inquiry
Human	COIL-2717H	Recombinant Human COIL protein, His & T7-tagged	E.coli	His/T7	Ser319~Glu538 (Accession # P38432)	Inquiry
Human	COIL-1633H	Recombinant Human COIL Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	COIL-7380HCL	Recombinant Human COIL 293 Cell Lysate	HEK293	N/A		Inquiry
Human	COIL-2746H	Recombinant Human COIL protein(131-240 aa), C-His-tagged	E. coli	C-His	131-240 aa	Inquiry
Human	COIL-2086HF	Recombinant Full Length Human COIL Protein, GST-tagged	In Vitro Cell Free System	GST	576 amino acids	Inquiry
Human	COIL-2231H	Recombinant Human COIL Protein (Ser319-Glu538), N-His tagged	E.coli	N-His	Ser319-Glu538	Inquiry
Rhesus Macaque	COIL-958R	Recombinant Rhesus monkey COIL Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	COIL-783R	Recombinant Rhesus Macaque COIL Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	COIL-783R-B	Recombinant Rhesus Macaque COIL Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	COIL-9061Z	Recombinant Zebrafish COIL	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
COIL Related Articles

COIL involved in several pathways and played different roles in them. We selected most pathways COIL participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with COIL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

COIL has several biochemical functions, for example, disulfide oxidoreductase activity, identical protein binding, protein C-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by COIL itself. We selected most functions COIL had, and list some proteins which have the same functions with COIL. You can find most of the proteins on our site.

Function	Related Protein
disulfide oxidoreductase activity	GRX2;TMX1;COIL;PDIA2;TXNL1;PDIA3;DNAJC10;TXN
identical protein binding	VIL1;FGFR1;DYNLT3;ALS2CL;TRIM21;FAS;TPCN1;EID3;CEACAM16
protein C-terminus binding	PXK;CTGF;CAV3;OPRL1;ID1;KSR1;ERCC2;AGO2;ABL1
protein binding	PPP2CA;HTRA3;EFS;Casp3;MAP4;GTPBP10;TJP1;POP4;MACF1

COIL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COIL here. Most of them are supplied by our site. Hope this information will be useful for your research of COIL.

VRK1; BYSL; XRCC5

Chung, J; Kang, JS; et al. Fast and continuous microorganism detection using aptamer-conjugated fluorescent nanoparticles on an optofluidic platform. BIOSENSORS & BIOELECTRONICS 67:303-308(2015).

Kuttel, MM; Jackson, GE; et al. Capsular polysaccharide conformations in pneumococcal serotypes 19F and 19A. CARBOHYDRATE RESEARCH 406:27-33(2015).