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COL8A1

  • Official Full Name

    collagen, type VIII, alpha 1

  • Overview

    This gene encodes one of the two alpha chains of type VIII collagen. The gene product is a short chain collagen and a major component of the basement membrane of the corneal endothelium. The type VIII collagen fibril can be either a homo- or a heterotrimer. Alternatively spliced transcript variants encoding the same isoform have been observed.
  • Synonyms

    COL8A1; collagen, type VIII, alpha 1; C3orf7, chromosome 3 open reading frame 7; collagen alpha-1(VIII) chain; MGC9568; C3orf7; CO8A1_HUMAN; Collagen alpha 1(VIII) chain [Precursor]; Endothelial collagen; Vastatin; OTTHUMP00000192896; OTTHUMP00000192897; collagen VIII, alpha-1 polypeptide; cell proliferation-inducing protein 41; smooth muscle cell-expressed and macrophage conditioned medium-induced protein smag-64;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rabbit
  • Rat
  • E.coli
  • HEK293
  • Mammalian Cell
  • Mammalian cells
  • C
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human COL8A1-11440H Recombinant Human COL8A1, His-tagged E.coli His 396-744a.a.
Human COL8A1-140H Recombinant Human COL8A1, His-tagged E.coli His Pro575~Pro743
Human COL8A1-7376HCL Recombinant Human COL8A1 293 Cell Lysate HEK293 N/A
Human COL8A1-1770H Recombinant Human COL8A1 Protein (Gly28-Met744), C-His tagged Mammalian cells C-His Gly28-Met744
Mouse COL8A1-3752M Recombinant Mouse COL8A1 Protein Mammalian Cell His
Mouse COL8A1-1873M-B Recombinant Mouse COL8A1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Col8a1-338M Recombinant Mouse Col8a1 Protein, His-tagged E.coli His Glu583~Pro743
Mouse COL8A1-1873M Recombinant Mouse COL8A1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Col8a1-339R Recombinant Rat Col8a1 Protein, His-tagged E.coli His Leu590~Met744
Rabbit COL8A1-823R Recombinant Rabbit COL8A1 Protein, His-tagged E.coli N-His Leu590-Met744
Chicken COL8A1-5533C Recombinant Chicken COL8A1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • COL8A1 Related Research Area

COL8A1 involved in several pathways and played different roles in them. We selected most pathways COL8A1 participated on our site, such as Assembly of collagen fibrils and other multimeric structures, Collagen biosynthesis and modifying enzymes, Collagen formation, which may be useful for your reference. Also, other proteins which involved in the same pathway with COL8A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Assembly of collagen fibrils and other multimeric structuresCD151;TLL1;PCOLCE;COL6A1;COL4A3;COL10A1;COL2A1;BMP1B;LOXL3
Collagen biosynthesis and modifying enzymesCOL11A1B;COL16A1;COL23A1;COL1A1;BMP1B;COL3A1;LEPREL1;SERPINH1;SERPINH1B
Collagen formationBMP1B;CTSS;COL4A6;EMID2;COL5A3A;COL11A1B;PCOLCE2B;ADAMTS3;COL2A1
Extracellular matrix organizationADAM9;MFAP4;COL8A2;COL4A6;TIMP2A;COL19A1;DDR2;TLL2;EFEMP1

COL8A1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by COL8A1 itself. We selected most functions COL8A1 had, and list some proteins which have the same functions with COL8A1. You can find most of the proteins on our site.

Function Related Protein
protein bindingPELI1;TSG101;JAM2;WAPAL;COL13A1;MAPK8;GZMA;HNRNPR;CNKSR1

COL8A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COL8A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of COL8A1.

KRTAP26-1; KRTAP10-7; KRTAP10-8; SP4; CREB5; REL

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