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CORO2A

Official Full Name

coronin, actin binding protein, 2A
Overview

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants.
Synonyms

CORO2A; coronin, actin binding protein, 2A; coronin-2A; coronin 2A; coronin like protein B; IR10; WD protein IR10; WD repeat protein 2; WDR2; WD-repeat protein 2; coronin-like protein B; WD repeat-containing protein 2; coronin, actin-binding protein, 2A;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Myc
DDK
MYC
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CORO2A-579H	Recombinant Human CORO2A	Mammalian Cell	His		Inquiry
Human	CORO2A-1727H	Recombinant Human CORO2A Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	CORO2A-11479H	Recombinant Human CORO2A, GST-tagged	E.coli	GST	293-523a.a.	$319 / 25ug
Human	CORO2A-7341HCL	Recombinant Human CORO2A 293 Cell Lysate	HEK293	N/A		Inquiry
Human	CORO2A-7342HCL	Recombinant Human CORO2A 293 Cell Lysate	HEK293	N/A		Inquiry
Human	CORO2A-1987HF	Recombinant Full Length Human CORO2A Protein, GST-tagged	In Vitro Cell Free System	GST	525 amino acids	Inquiry
Human	CORO2A-3330H	Recombinant Human CORO2A Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	CORO2A-2719H-B	Recombinant Human CORO2A Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Human	CORO2A-2719H	Recombinant Human CORO2A Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Coro2a-339M	Recombinant Mouse Coro2a Protein, MYC/DDK-tagged	HEK293T	MYC/DDK		Inquiry
Zebrafish	CORO2A-10044Z	Recombinant Zebrafish CORO2A	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

CORO2A involved in several pathways and played different roles in them. We selected most pathways CORO2A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CORO2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

CORO2A has several biochemical functions, for example, actin filament binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CORO2A itself. We selected most functions CORO2A had, and list some proteins which have the same functions with CORO2A. You can find most of the proteins on our site.

Function	Related Protein
actin filament binding	WIPF2B;SPTA1;ERMN;PLDN;TAGLN3B;ANTXR1;CTNNA3;TTN;WIPF1A

CORO2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CORO2A here. Most of them are supplied by our site. Hope this information will be useful for your research of CORO2A.

AURKA; BUB1; NRAS; RB1; DCC; SMAD2; q81wa0_bacan; q8d0h6_yerpe; ilvE; DLC1; MYO1C; FLNA; MYH9; IQGAP1; CAPZA2; Tpm1; Actb; DBN1; Myh10