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CR1

  • Official Full Name

    CR1 complement component (3b/4b) receptor 1 (Knops blood group)

  • Synonyms

    CR1; complement component (3b/4b) receptor 1 (Knops blood group); complement component (3b/4b) receptor 1, including Knops blood group system; complement receptor type 1; CD35; KN; CD35 antigen; C3b/C4b receptor; C3-binding protein; Knops blood group antigen; complement component receptor 1; C3BR; C4BR;

  • Recombinant Proteins
  • Therapeutic Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • E.coli
  • HEK293
  • Mammalian cells
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CR1-506H Active Recombinant Human CR1 protein, His-tagged Mammalian cells His
Human CR1-507H Recombinant Human CR1 Protein, His-tagged E.coli His Ile1780~Pro2039
Human CR1-P016H Recombinant Human CR1 therapeutic protein N/A
Human CR1-2727H Recombinant Human CR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CR1-2726H Recombinant Human CR1 protein, GST-tagged E.coli GST 41-234aa
Human CR1-4018H Recombinant Human CR1 Protein (Met1-Asp1971), C-His tagged Mammalian cells C-His Met1-Asp1971
Human CR1-2727H-B Recombinant Human CR1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CR1 Related Articles
  • CR1 Related Gene Family
  • CR1 Related Research Area

CR1 involved in several pathways and played different roles in them. We selected most pathways CR1 participated on our site, such as Complement and Coagulation Cascades, Complement cascade, Hematopoietic cell lineage, which may be useful for your reference. Also, other proteins which involved in the same pathway with CR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Complement and Coagulation CascadesSERPINA1;C5AR1;CFB;SERPINA1A;C6;SERPINA5;C4BPA;CD59A;C4BPB
Complement cascadeCFHL1;CFHL4;C1rb;FCN2;IgG3;MASP2;CFHL2;FCN3;HBL3
Hematopoietic cell lineageCD3D;Itga10&Itgb1;CD5;IL5RA;CD3G;CD4;CD7;CD44;CD1C
Immune SystemTREX1;OSCAR;RNF220;DEFA3;DEFB119;TNFSF13B;TRIM45;USP18;DEFB4A
Innate Immune SystemLRRFIP1;BTR16;CLEC4D;WIPF2;PPAPDC1B;TLR6;CASP4;TANK;RCA2.1
LegionellosisCR1;NAIP1;TLR2;Casp3;C3;EEF1A2;HSF1;APAF1;IL-8
LeishmaniasisITGB1;STAT1;MAPK13;TGFB3;IFNGR1;IFNG;ITGAM;IL12B;TGFB1

CR1 has several biochemical functions, for example, complement component C3b binding, complement component C3b receptor activity, complement component C4b binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CR1 itself. We selected most functions CR1 had, and list some proteins which have the same functions with CR1. You can find most of the proteins on our site.

Function Related Protein
complement component C3b bindingPHB;CR1
complement component C3b receptor activity
complement component C4b bindingCR1;MASP2
complement component C4b receptor activity
virus receptor activityHAVCR1;ITGB3;TFRC;GPR172B;NPC1;CD80;CCR5;HTR2A;CLDN1

CR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CR1.

purL; q7ara8_yerpe; ubiF; bioB; ypvA; pgl; lexA

Koechli, V; Klaeser, B; et al. Consolidation of first remission using radioimmunotherapy with yttrium-90-ibritumomab-tiuxetan in adult patients with Burkitt lymphoma. LEUKEMIA RESEARCH 39:307-310(2015).
Ogembo, JG; Muraswki, MR; et al. A chimeric EBV gp350/220-based VLP replicates the virion B-cell attachment mechanism and elicits long-lasting neutralizing antibodies in mice. JOURNAL OF TRANSLATIONAL MEDICINE 13:-(2015).
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