CS
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Official Full Name
citrate synthase
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Overview
The protein encoded by this gene is a Krebs tricarboxylic acid cycle enzyme that catalyzes the synthesis of citrate from oxaloacetate and acetyl coenzyme A. The enzyme is found in nearly all cells capable of oxidative metablism. This protein is nuclear encoded and transported into the mitochondrial matrix, where the mature form is found. -
Synonyms
CS; citrate synthase; citrate synthase, mitochondrial; mitochondrial; CISY_HUMAN; citrate synthetase;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Native Proteins
- Assay Kits
- Cynomolgus Monkey
- Human
- Mouse
- Pig
- Rat
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Human Cell
- In Vitro Cell Free System
- Insect Cell
- Mammalian Cell
- Porcine Heart
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- His|T7
- Myc
- DDK
- Myc|DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- CS Related Articles
CS involved in several pathways and played different roles in them. We selected most pathways CS participated on our site, such as 2-Oxocarboxylic acid metabolism, Biosynthesis of amino acids, Biosynthesis of antibiotics, which may be useful for your reference. Also, other proteins which involved in the same pathway with CS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| 2-Oxocarboxylic acid metabolism | CS;NAGS |
| Biosynthesis of amino acids | SDSL;GM5506;PFKP;BCAT1;CS;IDH3A;PGK2;TPI1A;GOT2A |
| Biosynthesis of antibiotics | EHHADH;DLAT;LDHAL6A;DAO1;PAICS;BPNT1;GPR19;AGXT;CTH |
| Carbon metabolism | FH;ADPGK;AMT;PKM;PFKP;GPIA;PGP;FBP1A;TALDO1 |
| Citrate cycle (TCA cycle) | DLST;SDHD;FH1;SDHA;SDHDB;ACO1;MDH2;PDHA1B;IDH3B |
| Citric acid cycle (TCA cycle) | CS;DLST |
| Glyoxylate and dicarboxylate metabolism | DHDPSL;GLUL;ANI_1_2390104;GLULB;ACO1;GRHPR;HAO2;SHMT2;GLYCTK |
| Metabolic pathways | ARSB;DPM2;CYP4A10;AKR1A1B;ENOPH1;GLCE;SAT2;PAFAH1B3;AMDHD1 |
CS has several biochemical functions, for example, citrate (Si)-synthase activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CS itself. We selected most functions CS had, and list some proteins which have the same functions with CS. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| citrate (Si)-synthase activity | |
| poly(A) RNA binding | YTHDF1;RBM12;EXOSC9;HNRNPF;NTPCR;DIMT1;SNRPD2;PATL1;SOSTDC1B |
CS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CS here. Most of them are supplied by our site. Hope this information will be useful for your research of CS.
SGK1; MCC; CHM; HLA-B; USP11; EIF6; ARF6; TAB2; TRAF6; ere_dna; ATF2; CLPP
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