CSE1L
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Official Full Name
CSE1 chromosome segregation 1-like
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Overview
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. -
Synonyms
CSE1L; CSE1 chromosome segregation 1-like (yeast); chromosome segregation 1 (yeast homolog) like; exportin-2; CAS; CSE1; XPO2; exp2; importin-alpha re-exporter; chromosome segregation 1-like protein; cellular apoptosis susceptibility protein; MGC117283; M;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- in vitro E. coli
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- His|SUMO
- SUMO
- Myc|DDK
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | CSE1L-1959H | Recombinant Human CSE1L Protein, GST-tagged | Wheat Germ | GST | ||
Human | CSE1L-9523HCL | Recombinant Human CSE1L Over-expression Cell Lysate | HEK293T | Myc/DDK | ||
Human | CSE1L-27394TH | Recombinant Human CSE1L | Wheat Germ | N/A | 100 amino acids | |
Human | CSE1L-9523H | Recombinant Human CSE1L protein, MYC/DDK-tagged | HEK293 | Myc/DDK | ||
Human | CSE1L-27953TH | Recombinant Human CSE1L | Wheat Germ | N/A | 195 amino acids | |
Human | CSE1L-212HFL | Recombinant Full Length Human CSE1L Protein, C-Flag-tagged | Mammalian cells | Flag | ||
Human | CSE1L-2732H | Recombinant Human CSE1L Protein (1-200 aa), His-SUMO-tagged | in vitro E. coli | His/SUMO | 1-200 aa | |
Human | CSE1L-95HF | Recombinant Full Length Human CSE1L Protein | In Vitro Cell Free System | 195 amino acids | ||
Human | CSE1L-670H-B | Recombinant Human CSE1L Protein Pre-coupled Magnetic Beads | HEK293 | |||
Human | CSE1L-670H | Recombinant Human CSE1L Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Human | CSE1L-2363H | Recombinant Human CSE1L protein, His-SUMO-tagged | E.coli | His-SUMO | 1-200aa | |
Human | CSE1L-2152HF | Recombinant Full Length Human CSE1L Protein, GST-tagged | In Vitro Cell Free System | GST | 195 amino acids | |
Rhesus Macaque | CSE1L-1049R | Recombinant Rhesus monkey CSE1L Protein, His-tagged | Mammalian Cell | His | ||
Rhesus Macaque | CSE1L-874R-B | Recombinant Rhesus Macaque CSE1L Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rhesus Macaque | CSE1L-874R | Recombinant Rhesus Macaque CSE1L Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Zebrafish | CSE1L-11497Z | Recombinant Zebrafish CSE1L | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
CSE1L involved in several pathways and played different roles in them. We selected most pathways CSE1L participated on our site, such as Direct p53 effectors, p53 pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CSE1L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Direct p53 effectors | PCBP4;DDX5;GDF15;DDB2;BNIP3L;FDXR;CEBPZ;PPM1J;RNF144B |
p53 pathway | NEDD8;SMYD2;HUWE1;KAT8;FBXO11;DYRK2;CSE1L;TTC5;TRIM28 |
CSE1L has several biochemical functions, for example, Ran GTPase binding, nuclear export signal receptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CSE1L itself. We selected most functions CSE1L had, and list some proteins which have the same functions with CSE1L. You can find most of the proteins on our site.
Function | Related Protein |
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Ran GTPase binding | RANGRF;TNPO2;XPO1;RANBP2;RANBP3;DPY19L2;KPNB1;NXT1;IPO4 |
nuclear export signal receptor activity | CSE1L;NUPL2;XPO7;XPO4 |
protein binding | TUFM;G3BP1;WDR77;GSE1;CCDC155;RARG;MAFB;RANGAP1;NGB |
CSE1L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CSE1L here. Most of them are supplied by our site. Hope this information will be useful for your research of CSE1L.
TP53; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate; LRRK2; USP19; TNFRSF1B; NRIP1; YWHAG; YWHAZ; IKBKG; HNRNPL; RPL22; PPP5C
- Q&As
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