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CSNK1E

  • Official Full Name

    casein kinase 1, epsilon

  • Overview

    The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene.
  • Synonyms

    CSNK1E; casein kinase 1, epsilon; casein kinase I isoform epsilon; CKIE; CKIepsilon; HCKIE; CKI-epsilon; MGC10398;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect (sf21)
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Sf9 Insect Cell
  • Wheat Germ
  • Yeast
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CSNK1E-27871TH Recombinant Human CSNK1E, His-tagged E.coli His
Human CSNK1E-1007H Recombinant Human Casein Kinase 1, Epsilon, GST-tagged Sf9 Insect Cell GST
Human CSNK1E-27754TH Recombinant Human CSNK1E Sf9 Insect Cell N/A 416 amino acids
Human CSNK1E-1994H Active Recombinant Human CSNK1E Protein, GST-tagged Insect Cell GST
Human CSNK1E-1995H Recombinant Human CSNK1E Protein, GST-tagged Wheat Germ GST
Human CSNK1E-7239HCL Recombinant Human CSNK1E 293 Cell Lysate HEK293 N/A
Human CSNK1E-7240HCL Recombinant Human CSNK1E 293 Cell Lysate HEK293 N/A
Human CSNK1E-764HFL Recombinant Full Length Human CSNK1E Protein, C-Flag-tagged Mammalian cells Flag
Human CSNK1E-1370H Recombinant Human CSNK1E Protein (1-416 aa), His-tagged Yeast His 1-416 aa
Human CSNK1E-2022HF Active Recombinant Full Length Human CSNK1E Protein, GST-tagged Insect (sf21) GST 1-348
Human CSNK1E-1183H Recombinant Human CSNK1E Protein (17-231 aa), GST-tagged E.coli GST 17-231 aa
Human CSNK1E-2192HF Recombinant Full Length Human CSNK1E Protein, GST-tagged In Vitro Cell Free System GST 416 amino acids
Human CSNK1E-2746H Recombinant Human CSNK1E protein, His-tagged E.coli His 1-416aa
Human CSNK1E-0202H Recombinant Human CSNK1E Protein (E2-K416), Tag Free Insect Cell No tag E2-K416
Human CSNK1E-2289H Recombinant Human CSNK1E Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CSNK1E-0203H Recombinant Human CSNK1E Protein (E2-K416), GST tagged Insect Cell GST E2-K416
Human CSNK1E-673H-B Recombinant Human CSNK1E Protein Pre-coupled Magnetic Beads HEK293
Human CSNK1E-2372H Recombinant Human CSNK1E Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CSNK1E-673H Recombinant Human CSNK1E Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CSNK1E-1060R Recombinant Rhesus monkey CSNK1E Protein, His-tagged Mammalian Cell His
Rhesus Macaque CSNK1E-885R Recombinant Rhesus Macaque CSNK1E Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CSNK1E-885R-B Recombinant Rhesus Macaque CSNK1E Protein Pre-coupled Magnetic Beads HEK293
Zebrafish CSNK1E-12017Z Recombinant Zebrafish CSNK1E Mammalian Cell His
Chicken CSNK1E-5947C Recombinant Chicken CSNK1E Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CSNK1E Related Articles
  • CSNK1E Related Research Area

CSNK1E involved in several pathways and played different roles in them. We selected most pathways CSNK1E participated on our site, such as Anchoring of the basal body to the plasma membrane, Assembly of the primary cilium, Canonical Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CSNK1E were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Anchoring of the basal body to the plasma membraneCCDC41;B9D2;CETN2;CC2D2A;MARK4;CSNK1D;CCP110;NINL;NEDD1
Assembly of the primary ciliumIFT52;RP2;KIF3A;SSNA1;ARL3;CNGA2;TCTEX1D1;CEP164;PKD1
Canonical Wnt signaling pathwayDVL2;DVL1;KLHL12;CSNK1A1;CSNK1E;CSNK1D;DVL3
Cell CycleCDKN2B;CCDC99;SKP1;TUBGCP3;SMAD3A;AHCTF1;CENPC1;HDAC2;SFN
Cell Cycle, MitoticMASTL;TOP2A;TUBG1;SET;VRK2;DSN1;KIF2C;LIN9;TCTN2
Centrosome maturationCLASP1A;CEP78;CEP152;MAPRE1;NDE1;CETN2;CEP290;TUBGCP4;NUMA1
Circadian ClockDBP;CRY2;NRIP1;HELZ2;CSNK1E;CARM1;CPT1A;NAMPT;CRY1
Circadian rhythmCRY1;PRKAA2;RORB;PRKAG2;PER2;PRKAG3;PRKAA1;PER3;CRY2

CSNK1E has several biochemical functions, for example, ATP binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CSNK1E itself. We selected most functions CSNK1E had, and list some proteins which have the same functions with CSNK1E. You can find most of the proteins on our site.

Function Related Protein
ATP bindingNTPCR;SKIV2L2;CKBA;PAK3;MYH4;MAP2K4A;CLK4;ACACB;PANK2
poly(A) RNA bindingDAZAP1;SNRPA;POU5F1;GNB2L1;ETF1;RPS6;HIST1H47;SF3A2;CCDC55
protein bindingFABP1;ZFAND2B;KCP;SNX2;DDX5;GAPDH;WDFY2;PPP2R3C;TRPC1
protein kinase activityMKNK2A;PTK2BB;CAMK1GB;RLN1;NRBP2;PANK1A;PRKCG;PIK3R4;DYRK1A
protein serine/threonine kinase activityPRKCA;LMTK3;CASK;FAM20C;MAP2K3;STK38L;MKNK2;ULK1A;CDC7

CSNK1E has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CSNK1E here. Most of them are supplied by our site. Hope this information will be useful for your research of CSNK1E.

MCC; APC; OCLN; AXIN1

Gonzalez-Sancho, JM; Greer, YE; et al. Functional Consequences of Wnt-induced Dishevelled 2 Phosphorylation in Canonical and Noncanonical Wnt Signaling. JOURNAL OF BIOLOGICAL CHEMISTRY 288:9428-9437(2013).
Shanware, NP; Hutchinson, JA; et al. Casein Kinase 1-dependent Phosphorylation of Familial Advanced Sleep Phase Syndrome-associated Residues Controls PERIOD 2 Stability. JOURNAL OF BIOLOGICAL CHEMISTRY 286:-(2011).
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