CST5
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Official Full Name
cystatin D
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Overview
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein found in saliva and tears. The encoded protein may play a protective role against proteinases present in the oral cavity. -
Synonyms
CST5; cystatin D; cystatin-D; CST 5; Cystatin 5; CystatinD; Cysteine proteinase inhibitor; MGC71922; cystatin-5; cysteine-proteinase inhibitor;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- E.coli
- HEK293
- Human Cell
- In Vitro Cell Free System
- Insect Cell
- Mammalian cells
- Wheat Germ
- C
- His
- GST
- His (Fc)
- Avi
- His|T7
- N/A
- N
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | CST5-494H | Active Recombinant Human CST5, His-tagged | Mammalian cells | His |
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| Human | CST5-2028H | Recombinant Human CST5 Protein, GST-tagged | Wheat Germ | GST |
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| Human | CST5-675H | Recombinant Human CST5 protein, His-tagged | HEK293 | His | Gly21-Val142 | |
| Human | CST5-102H | Recombinant Human CST5, His-tagged | Insect Cell | His |
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| Human | CST5-3027HCL | Recombinant Human CST5 cell lysate | Human Cell | N/A |
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| Human | CST5-2745H-B | Recombinant Human CST5 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Human | CST5-1663H | Recombinant Human CST5 protein, His & T7-tagged | E.coli | His/T7 | Gly21~Val142 (Accession # P28325) |
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| Human | CST5-2238HF | Recombinant Full Length Human CST5 Protein, GST-tagged | In Vitro Cell Free System | GST | 142 amino acids |
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| Human | CST5-2745H | Recombinant Human CST5 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Human | CST5-187H | Recombinant Human CST5 Protein, His-tagged | HEK293 | His | 142 |
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| Human | CST5-1856H | Recombinant Human CST5 Protein (Gly21-Val142), N-His tagged | E.coli | N-His | Gly21-Val142 |
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| Human | CST5-1854H | Recombinant Human CST5 protein(Met1-Val142), His-tagged | HEK293 | C-His | Met1-Val142 |
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- Involved Pathway
- Protein Function
- Interacting Protein
- CST5 Related Articles
CST5 involved in several pathways and played different roles in them. We selected most pathways CST5 participated on our site, such as Endochondral Ossification, Salivary secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with CST5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Endochondral Ossification | COL2A1;ADAMTS5;NKX3.2;IFT88;CDKN1C;RUNX3;PTH;CST5;CTSL2 |
| Salivary secretion | PRKG2;NOS1;ATP1A2;AQP5;GNAS;ATP1A1;PRB1;PRH2;PRKCB |
CST5 has several biochemical functions, for example, cysteine-type endopeptidase inhibitor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CST5 itself. We selected most functions CST5 had, and list some proteins which have the same functions with CST5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cysteine-type endopeptidase inhibitor activity | NAIP1;CST1;KNG1;BIRC7;CST8;HRG;CST9;BIRC5B;Cstb |
| protein binding | TRPC1;CD63;CRMP1;MSR1;NUAK1;IL23R;RIPPLY2;TP73;INCA1 |
CST5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CST5 here. Most of them are supplied by our site. Hope this information will be useful for your research of CST5.
- Q&As
- Reviews
Q&As (7)
Ask a questionChanges in CST5 expression can affect skin health, playing a role in skin cell turnover and the development of skin disorders.
CST5 inhibits cysteine proteases, playing a crucial role in regulating protease activity and preventing uncontrolled protein degradation.
CST5 is involved in immune regulation, modulating inflammatory responses and protecting against excessive inflammation.
CST5 contributes to oral health by inhibiting proteases that can lead to periodontal disease.
CST5 influences bone remodeling, potentially affecting the development of osteoporosis by regulating bone resorption.
CST5 may impact neurodegenerative diseases by modulating protease activity, which is important in protein aggregation and neuronal health.
CST5 helps prevent cancer progression by inhibiting tumor cell invasion and metastasis through protease regulation.
Customer Reviews (3)
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