CTAG2
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Official Full Name
cancer/testis antigen 2
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Overview
This gene encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID 10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants. -
Synonyms
CTAG2; cancer/testis antigen 2; CAMEL; cancer/testis antigen family 6; member 2a; member 2b; CT6.2a; CT6.2b; CTL recognized antigen on melanoma; ESO2; LAGE 1; LAGE 1a; LAGE 1a protein; LAGE 1b; LAGE1; MGC3803; MGC138724; Autoimmunogenic cancer/testis antigen NY ESO 2; Autoimmunogenic cancer/testis antigen NY-ESO-2; Cancer/testis antigen 6.2; CT 2; CT2; CT6.2; CTAG 2; CTAG2_HUMAN; ESO 2; L antigen family member 1; LAGE 2b; LAGE-1; LAGE2b; LAGE-1a protein; OTTHUMP00000026043; OTTHUMP00000026044; CTL-recognized antigen on melanoma; cancer/testis antigen family 6, member 2a; cancer/testis antigen family 6, member 2b; autoim;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | CTAG2-492H | Recombinant Human CTAG2, His-tagged | E.coli | His | 1-210aa | |
| Human | CTAG2-7217HCL | Recombinant Human CTAG2 293 Cell Lysate | HEK293 | N/A |
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| Human | CTAG2-2471H | Recombinant Human CTAG2 Protein (1-210 aa), His-sumostar-tagged | Yeast | His/SUMOstar | 1-210 aa |
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| Human | CTAG2-2751H | Recombinant Human CTAG2 protein, His-SUMO-tagged | E.coli | His-SUMO | 1-210aa |
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| Human | CTAG2-146H | Recombinant Human CTAG2 Protein, MYC/DDK-tagged, C13 and N15-labeled | HEK293 | C-Myc/DDK |
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- Involved Pathway
- Protein Function
- Interacting Protein
- CTAG2 Related Research Area
CTAG2 involved in several pathways and played different roles in them. We selected most pathways CTAG2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CTAG2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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CTAG2 has several biochemical functions, for example, molecular_function, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CTAG2 itself. We selected most functions CTAG2 had, and list some proteins which have the same functions with CTAG2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| molecular_function | AMTN;TAS2R124;TMEM9;GRAMD1A;KDELC2;IFT80;TMEM30AB;TIAF1;GM10230 |
| protein binding | KRTAP3-3;MINK1;NOC2L;HFE2;GABRG2;MAP2K5;SERPINI2;PRICKLE1A;LOXL2 |
CTAG2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CTAG2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CTAG2.
TRIP6; UBQLN1; Bag2
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