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CTF1

  • Official Full Name

    cardiotrophin 1

  • Overview

    The protein encoded by this gene is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
  • Synonyms

    CTF1; cardiotrophin 1; CT1; CT-1; cardiotrophin-1; cardiophin 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • CHO
  • E.coli
  • HEK293
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mouse
  • Sf21 Insect Cell
  • Wheat Germ
  • Fc
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
  • N
  • Strep II
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CTF1-184H Active Recombinant Human Cardiotrophin 1, GST-tagged E.coli GST
Human CTF1-122H Active Recombinant Human CTF1 protein E.coli N/A
Human CTF1-8450H Active Recombinant Human CTF1, His-tagged Sf21 Insect Cell His
Human CTF1-239H Recombinant Human CTF1, Fc-tagged Human Cell Fc Ser2-Ala201
Human CTF1-238H Active Recombinant Human CTF1 protein(Ser2-Ala201) HEK293 N/A Ser2-Ala201
Human CTF1-2067H Recombinant Human CTF1 Protein, GST-tagged Wheat Germ GST
Human CTF1-138H Recombinant Human CTF1 protein E.coli N/A 201
Human CTF1-251H Recombinant Human CTF1, StrepII-tagged Human Cell Strep II 1-201, 201 a.a.
Human CTF1-136H Recombinant Human Cardiotrophin-1, His-tagged E.coli His
Human CTF1-001HCL Recombinant Human CTF1 cell lysate Human Cell N/A
Human CTF1-2276HF Recombinant Full Length Human CTF1 Protein, GST-tagged In Vitro Cell Free System GST 201 amino acids
Human CTF1-137H Recombinant Human CTF1 protein, His-tagged E.coli His Met1-Ala201
Human CTF1-295C Active Recombinant Human CTF1 Protein (201 aa) CHO 201
Mouse Ctf1-342M Active Recombinant Mouse Cardiotrophin 1 Mouse N/A
Mouse Ctf1-183M Recombinant Murine Cardiotrophin 1 E.coli N/A
Mouse Ctf1-658M Recombinant Mouse Ctf1 protein E.coli N/A 203
Mouse Ctf1-1286M Recombinant Mouse Ctf1 Protein, His-tagged E.coli N-His Met1-Ala203
Mouse Ctf1-191C Active Recombinant Mouse Ctf1 Protein (202 aa) HEK293 202
Mouse Ctf1-049M Active Recombinant Mouse Ctf1 Protein E.coli
Rat Ctf1-7733R Recombinant Rat Ctf1 protein, His & T7-tagged E.coli His/T7 Met1~Ala203 (Accession # Q63086)
Rat CTF1-1653R Recombinant Rat CTF1 Protein Mammalian Cell His
Rat Ctf1-1174R Recombinant Rat Ctf1 protein E.coli N/A 203
Rat CTF1-1312R-B Recombinant Rat CTF1 Protein Pre-coupled Magnetic Beads HEK293
Rat CTF1-1312R Recombinant Rat CTF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CTF1 Related Research Area

CTF1 involved in several pathways and played different roles in them. We selected most pathways CTF1 participated on our site, such as Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, MicroRNAs in cardiomyocyte hypertrophy, which may be useful for your reference. Also, other proteins which involved in the same pathway with CTF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionIL2RA;TNFSF8;CCL21B;Cxcl15;CXCR4A;PLEKHO2;KDRL;PRP2;PDGFC
Jak-STAT signaling pathwayPTPN6;PIK3CD;AKT2;LEPR;SOCS6;IL12A;IFNGR1;AOX4;IFNA14
MicroRNAs in cardiomyocyte hypertrophyRCAN1;MYEF2;CTF1
Physiological and Pathological Hypertrophy of the HeartMYEF2;CTF1

CTF1 has several biochemical functions, for example, cytokine activity, leukemia inhibitory factor receptor binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CTF1 itself. We selected most functions CTF1 had, and list some proteins which have the same functions with CTF1. You can find most of the proteins on our site.

Function Related Protein
cytokine activityMSTN;CXCL9;TIMP1;GDF7;IL17B;GDF1;IL17A/F2;CMTM7;IL1F10
leukemia inhibitory factor receptor bindingLIF;Ctf2;CTF1
protein bindingGRIA2;KAT2A;CTLA4;ITGA3;EIF2S2;KDR;BCL2L14;CNTROB;DDIT3

CTF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CTF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CTF1.

MAGEA6

  • Q&As
  • Reviews

Q&As (7)

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How does CTF1 contribute to metabolic regulation, particularly in obesity and diabetes? 10/22/2022

CTF1 plays a role in metabolic regulation, impacting processes related to obesity and diabetes.

What are the effects of CTF1 on neuronal survival and regeneration in neurodegenerative diseases? 05/20/2022

CTF1 supports neuronal survival and regeneration, offering potential benefits in neurodegenerative conditions.

How does CTF1 influence cardiac hypertrophy and heart failure progression? 04/22/2022

CTF1 promotes cardiac hypertrophy and can contribute to heart failure progression by influencing heart muscle cell growth.

How do alterations in CTF1 expression affect tissue repair and regeneration after injury? 05/16/2021

Changes in CTF1 expression are important for tissue repair and regeneration, particularly following injury.

What role does CTF1 play in the regulation of muscle regeneration and muscle wasting diseases? 08/05/2020

CTF1 aids in muscle regeneration and can be involved in the pathology of muscle wasting diseases.

How does CTF1 interact with the JAK/STAT signaling pathway in different cell types? 08/25/2019

CTF1 activates the JAK/STAT signaling pathway, affecting cell growth, differentiation, and survival.

What is the impact of CTF1 in inflammatory responses and autoimmune diseases? 08/14/2019

CTF1 influences inflammatory and immune responses, potentially impacting autoimmune disease mechanisms.

Customer Reviews (3)

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Reviews
08/19/2022

    Swift protein characterization services; key for our research projects.

    09/28/2019

      Expertise in protein engineering; invaluable for our lab's needs.

      08/31/2019

        High-quality protein-protein interaction assays; essential for our experiments.

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