CTF1
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Official Full Name
cardiotrophin 1
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Overview
The protein encoded by this gene is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] -
Synonyms
CTF1; cardiotrophin 1; CT1; CT-1; cardiotrophin-1; cardiophin 1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- CHO
- E.coli
- HEK293
- Human Cell
- In Vitro Cell Free System
- Mammalian Cell
- Mouse
- Sf21 Insect Cell
- Wheat Germ
- Fc
- GST
- His
- His (Fc)
- Avi
- His|T7
- N/A
- N
- Strep II
- Involved Pathway
- Protein Function
- Interacting Protein
- CTF1 Related Research Area
CTF1 involved in several pathways and played different roles in them. We selected most pathways CTF1 participated on our site, such as Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, MicroRNAs in cardiomyocyte hypertrophy, which may be useful for your reference. Also, other proteins which involved in the same pathway with CTF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Cytokine-cytokine receptor interaction | IL2RA;TNFSF8;CCL21B;Cxcl15;CXCR4A;PLEKHO2;KDRL;PRP2;PDGFC |
Jak-STAT signaling pathway | PTPN6;PIK3CD;AKT2;LEPR;SOCS6;IL12A;IFNGR1;AOX4;IFNA14 |
MicroRNAs in cardiomyocyte hypertrophy | RCAN1;MYEF2;CTF1 |
Physiological and Pathological Hypertrophy of the Heart | MYEF2;CTF1 |
CTF1 has several biochemical functions, for example, cytokine activity, leukemia inhibitory factor receptor binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CTF1 itself. We selected most functions CTF1 had, and list some proteins which have the same functions with CTF1. You can find most of the proteins on our site.
Function | Related Protein |
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cytokine activity | MSTN;CXCL9;TIMP1;GDF7;IL17B;GDF1;IL17A/F2;CMTM7;IL1F10 |
leukemia inhibitory factor receptor binding | LIF;Ctf2;CTF1 |
protein binding | GRIA2;KAT2A;CTLA4;ITGA3;EIF2S2;KDR;BCL2L14;CNTROB;DDIT3 |
CTF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CTF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CTF1.
MAGEA6
- Q&As
- Reviews
Q&As (7)
Ask a questionCTF1 plays a role in metabolic regulation, impacting processes related to obesity and diabetes.
CTF1 supports neuronal survival and regeneration, offering potential benefits in neurodegenerative conditions.
CTF1 promotes cardiac hypertrophy and can contribute to heart failure progression by influencing heart muscle cell growth.
Changes in CTF1 expression are important for tissue repair and regeneration, particularly following injury.
CTF1 aids in muscle regeneration and can be involved in the pathology of muscle wasting diseases.
CTF1 activates the JAK/STAT signaling pathway, affecting cell growth, differentiation, and survival.
CTF1 influences inflammatory and immune responses, potentially impacting autoimmune disease mechanisms.
Customer Reviews (3)
Write a reviewSwift protein characterization services; key for our research projects.
Expertise in protein engineering; invaluable for our lab's needs.
High-quality protein-protein interaction assays; essential for our experiments.
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