Ctsz
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Official Full Name
cathepsin Z
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Overview
The protein encoded by this gene is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The encoded protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis. -
Synonyms
CTSZ; cathepsin Z; Cathepsin P; Cathepsin X; Cathepsin X precursor; Cathepsin Z precursor; CathepsinP; CathepsinX; CathepsinZ; CATZ_HUMAN; CTSX; FLJ17088; Preprocathepsin P; PreprocathepsinP; OTTHUMP00000031409;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Human Cell
- In Vitro Cell Free System
- Insect Cell
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- C
- His
- GST
- His (Fc)
- Avi
- His|T7
- Myc
- DDK
- Myc|DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- Ctsz Related Articles
- Ctsz Related Research Area
Ctsz involved in several pathways and played different roles in them. We selected most pathways Ctsz participated on our site, such as Asparagine N-linked glycosylation, COPII (Coat Protein 2) Mediated Vesicle Transport, Cargo concentration in the ER, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ctsz were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Asparagine N-linked glycosylation | TRAPPC3;TRAPPC6B;OS9;ANKRD28;SERPINA1L;CTAGE5;ST8SIA3;LMAN2L;NAPG |
COPII (Coat Protein 2) Mediated Vesicle Transport | NSFB;TRAPPC2L;CTSZ;TRAPPC6B;TRAPPC6BL;TRAPPC5;CSNK1D;TRAPPC1;BET1 |
Cargo concentration in the ER | AREG;TMED2;SEC23A;CNIH;MIA3;SEC24A;PREB;LMAN2;CTSZ |
Clathrin derived vesicle budding | SNX9;PICALMB;AP1M2;NECAP1;GAK;AP3S1;BLOC1S6;APPB;FTH1A |
ER to Golgi Anterograde Transport | SEC24A;GORASP1;MIA3;TFG;NSFA;SCFD1;CNIH2;TRAPPC6BL;TRAPPC6B |
Lysosome | CD68;GLA;SORT1;CLTCA;NAGA;SMPD1;GGA2;AP3B1;DNASE2B |
Lysosome Vesicle Biogenesis | BLOC1S1;CTSZ;DNASE2;AP1S3A;CLVS2;AP4B1;CLVS1 |
Membrane Trafficking | DAB2;PICALMB;PREB;MYO1C;AP4B1;GJB7;TRAPPC6A;DNASE2;CNIH |
Ctsz has several biochemical functions, for example, cysteine-type endopeptidase activity, cysteine-type peptidase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Ctsz itself. We selected most functions Ctsz had, and list some proteins which have the same functions with Ctsz. You can find most of the proteins on our site.
Function | Related Protein |
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cysteine-type endopeptidase activity | CTSL.1;CTSC;SFRP1;CTSO;USP34;USP50;CTSF;CASPBL;CTSZ |
cysteine-type peptidase activity | USP17L1P;ESPL1;CTSSB.2;CTSM;CAPN2L;ATG4A;USP9X;ZRANB1B;CTSBB |
protein binding | PIM1;ZFP523;MYO10;INPP5A;SLC9A3R1;TRIM11;SAP30;CFLAR;SMN1 |
Ctsz has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ctsz here. Most of them are supplied by our site. Hope this information will be useful for your research of Ctsz.
KRTAP5-9; PLSCR1; MTUS2; KRT40; NOTCH2NL; MID2; Kifc5b
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