CYSLTR2
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Official Full Name
cysteinyl leukotriene receptor 2
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Overview
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR1. This encoded receptor is a member of the superfamily of G protein-coupled receptors. It seems to play a major role in endocrine and cardiovascular systems. -
Synonyms
CYSLTR2; cysteinyl leukotriene receptor 2; CysLT(2); CYSLT2R; CLTR2_HUMAN; CYSLTR 2; Cysteinyl leukotriene CysLT2 receptor; G protein coupled receptor; G protein coupled receptor GPCR21; G protein coupled receptor HG57; G-protein coupled receptor GPCR21; G-protein coupled receptor HG57; GPCR; HG57; hGPCR21; HPN321; PSEC0146; G protein-coupled receptor; CYSLT2; KPG_011;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- Sus scrofa (Pig)
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- His
- His (Fc)
- Avi
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
CYSLTR2 involved in several pathways and played different roles in them. We selected most pathways CYSLTR2 participated on our site, such as Calcium signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYSLTR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Calcium signaling pathway | HTR2A;ATP2B1;CD38;PDE1C;CALM3;GNA14;ITPR3;RYR2;VDAC3 |
| Neuroactive ligand-receptor interaction | RXFP4;GRM1;LEP;CYSLTR2;OPRL1;HTR1AA;AVPR1A;MLNR;GHRHR |
CYSLTR2 has several biochemical functions, for example, G-protein coupled peptide receptor activity, cysteinyl leukotriene receptor activity, leukotriene receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CYSLTR2 itself. We selected most functions CYSLTR2 had, and list some proteins which have the same functions with CYSLTR2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein coupled peptide receptor activity | GPR84;LTB4R;MCHR2;LTB4R2;RXFP4;NPR1;TSHR;LHCGR;RXFP3.2B |
| cysteinyl leukotriene receptor activity | CYSLTR2;MCHR2;CYSLTR1 |
| leukotriene receptor activity | CYSLTR1;LTB4R;CYSLTR2;LTB4R2 |
| protein binding | LRRC75A-AS1;DKK1;MOV10;APBB1;NLRC4;TBC1D15;CDC25C;ADRBK1;H2AFY |
CYSLTR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYSLTR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYSLTR2.
CYSLTR1; DLG1
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