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Cdh3

  • Official Full Name

    cadherin 3, type 1, P-cadherin (placental)

  • Overview

    This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.
  • Synonyms

    CDH3; cadherin 3, type 1, P-cadherin (placental); CDHP; HJMD; PCAD;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Pig
  • E. coli
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mamanlian cells
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Yeast
  • C
  • Fc
  • His
  • Flag
  • GST
  • His (Fc)
  • Avi
  • His|Fc
  • His|GST
  • SUMOstar
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
  • T7|His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CDH3-488H Active Recombinant Human CDH3 protein, His/Fc-tagged Mammalian cells His/Fc
Human CDH3-281H Recombinant Human CDH3, T7/His-tagged E.coli T7/His
Human CDH3-168H Recombinant Human CDH3, His-tagged HEK293 His
Human CDH3-5724H Recombinant Human CDH3 protein, His-tagged E.coli His Gly371~Leu660 (Accession # P22223)
Human Cdh3-1673M Recombinant Mouse Cdh3 protein, Fc-tagged HEK293 N/A Glu100-Gly647
Human CDH3-289H Recombinant Human CDH3, MYC/DDK-tagged HEK293 Myc/DDK
Human CDH3-0989H Recombinant Human CDH3 Protein, GST-Tagged Wheat Germ GST
Human CDH3-7636HCL Recombinant Human CDH3 293 Cell Lysate HEK293 N/A
Human CDH3-2696H Recombinant Human CDH3 protein(681-780 aa), C-His-tagged E. coli C-His 681-780 aa
Human CDH3-3149HF Recombinant Full Length Human CDH3 Protein, GST-tagged In Vitro Cell Free System GST 829 amino acids
Human CDH3-5818H Recombinant Human CDH3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CDH3-169H Recombinant Human CDH3 protein, His-tagged HEK293 His Asp 108 - Gly 654
Human CDH3-4101HFL Recombinant Full Length Human CDH3, Flag-tagged Mamanlian cells Flag
Human CDH3-4347H Recombinant Human CDH3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CDH3-4347H-B Recombinant Human CDH3 Protein Pre-coupled Magnetic Beads HEK293
Human CDH3-0272H Recombinant Human CDH3 Protein (Glu25-Gly654), C-His-tagged Mammalian cells C-His Glu25-Gly654
Human CDH3-0809H Recombinant Human CDH3 Protein (Gly371-Leu660), His tagged E.coli His Gly371-Leu660
Mouse Cdh3-5726M Recombinant Mouse Cdh3 protein, His & GST-tagged E.coli His/GST Ser565~Asp822 (Accession # P10287)
Mouse Cdh3-5725M Recombinant Mouse Cdh3 protein, His-tagged E.coli His Lys154~Asp394 (Accession # P10287)
Mouse CDH3-3177M Recombinant Mouse CDH3 Protein Mammalian Cell His
Mouse Cdh3-5626M Recombinant Mouse Cdh3 Protein (Glu100-Gly647), C-Fc tagged Mammalian cells C-Fc Glu100-Gly647
Mouse CDH3-1509M Recombinant Mouse CDH3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Cdh3-862M Recombinant Mouse Cdh3 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse CDH3-1509M-B Recombinant Mouse CDH3 Protein Pre-coupled Magnetic Beads HEK293
Homo sapiens (Human) RFL32428HF Recombinant Full Length Human Cadherin-3(Cdh3) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (108-829)
Mus musculus (Mouse) RFL7218MF Recombinant Full Length Mouse Cadherin-3(Cdh3) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (100-822)
Pig CDH3-2232P Recombinant Pig CDH3 Protein (1-145 aa), His-tagged Yeast His 1-145 aa
Pig CDH3-5376P Recombinant Pig CDH3 protein, His-SUMOstar-tagged Yeast His-SUMOstar 1-145aa
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Cdh3 Related Articles
  • Cdh3 Related Research Area

Cdh3 involved in several pathways and played different roles in them. We selected most pathways Cdh3 participated on our site, such as Adherens junctions interactions, Cell adhesion molecules (CAMs), Cell junction organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cdh3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adherens junctions interactionsANG;CDH10;CADM2;CDH9;CDH18;CDH2;CDH10A;CDH12A;CDH18A
Cell adhesion molecules (CAMs)ICOS;ITGA9;CLDN1;BF1;H2-Q10;CLDN19;CDH5;CNTNAP1;NEGR1
Cell junction organizationANG;COL17A1A;CDH24;CDH17;CLDN3;CDH12;CD151;TESK1;CLDN23
Cell-Cell communicationCD151;LIMS1;KIRREL;ANG;CLDN7;CDH10;SKAP2;CLDN4;FBLIM1
Cell-cell junction organizationCDH10A;INADL;CDH5;PVRL2L;CADM2A;PVRL1A;CDH12;CLDN20;CDH6

Cdh3 has several biochemical functions, for example, calcium ion binding, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by Cdh3 itself. We selected most functions Cdh3 had, and list some proteins which have the same functions with Cdh3. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingPRRG4;PKD1L2;EFHD2;MBL1;DLC;MAN1A2;CDH19;F9A;CUBN
molecular_functionTMEM39B;COMMD4;FAM40A;FLOT2A;DONSON;CUEDC1B;NEURL4;TM7SF3;ARL6IP5B

Cdh3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cdh3 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cdh3.

IGF1R; q7ard3_yerpe; y551_bacan; YAP1; AP2M1

Watson, S; Sarris, M; et al. Limbal Dermoid Epithelium Shares Phenotypic Characteristics Common to Both Hair Epidermal and Limbal Epithelial Stem Cells. CURRENT EYE RESEARCH 38:835-842(2013).
Yoshioka, H; Yamamoto, S; et al. In vivo therapeutic effect of CDH3/P-cadherin-targeting radioimmunotherapy. CANCER IMMUNOLOGY IMMUNOTHERAPY 61:1211-1220(2012).
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