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Cep63

Official Full Name

CEP63 centrosomal protein 63kDa [ Homo sapiens ]
Overview

This gene encodes a protein with six coiled-coil domains. The protein is localized to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. Several alternatively spliced transcript variants have been found, but their biological validity has not been determined.
Synonyms

centrosomal protein 63kDa; FLJ13386; centrosomal protein of 63 kDa; centrosome protein CEP63; Cep63;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Rat
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
SUMO
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CEP63-11114H	Recombinant Human CEP63, GST-tagged	E.coli	GST	1-349a.a.	$319 / 25ug
Human	CEP63-1138H	Recombinant Human CEP63 Protein, GST-Tagged	Wheat Germ	GST		Inquiry
Human	CEP63-7571HCL	Recombinant Human CEP63 293 Cell Lysate	HEK293	N/A		Inquiry
Human	CEP63-4676H	Recombinant Human CEP63 protein, His-SUMO-tagged	E.coli	His-SUMO	1-495aa	Inquiry
Human	CEP63-3210H	Recombinant Human CEP63 Protein, His-tagged	E.coli	His		Inquiry
Human	CEP63-3238HF	Recombinant Full Length Human CEP63 Protein, GST-tagged	In Vitro Cell Free System	GST	541 amino acids	Inquiry
Rat	CEP63-1345R	Recombinant Rat CEP63 Protein	Mammalian Cell	His		Inquiry
Rat	CEP63-1003R-B	Recombinant Rat CEP63 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	CEP63-1003R	Recombinant Rat CEP63 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Zebrafish	CEP63-10880Z	Recombinant Zebrafish CEP63	Mammalian Cell	His		Inquiry
Chicken	CEP63-4039C	Recombinant Chicken CEP63	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Cep63 Related Articles

Cep63 involved in several pathways and played different roles in them. We selected most pathways Cep63 participated on our site, such as Anchoring of the basal body to the plasma membrane, Assembly of the primary cilium, Cell Cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cep63 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Anchoring of the basal body to the plasma membrane	CDK5RAP2;PLK4;MAPRE1B;CEP70;ACTR1A;TCTN3;OFD1;TUBB4A;CEP63
Assembly of the primary cilium	LZTFL1;CKAP5;CETN2;CEP97;TCTN1;OFD1;IFT46;PKD1;CEP152
Cell Cycle	CEP70;CDK7;RBL1;TUBB4A;GMNN;MAPRE1A;TOP2A;TGFB2;BUB3
Cell Cycle, Mitotic	DULLARD;MYBL2;TUBGCP4;CTDNEP1B;ENSAB;SETB;LIN52;SET;MAU2
Centrosome maturation	TUBGCP2;CEP76;CLASP1A;TUBB4B;CEP57;TUBGCP3;DYNC1I2;NINL;HAUS2
G2/M Transition	LIN37;OFD1;DCTN1A;NDE1;BORA;DCTN2;NINL;ACTR1A;CEP290
Loss of Nlp from mitotic centrosomes	CEP70;ODF2B;TUBG1;OFD1;DCTN1A;CEP72;CEP164;TSGA14;MAPRE1B
Loss of proteins required for interphase microtubule organizationfrom the centrosome	CEP57;MAPRE1A;CLASP1A;CEP63;CEP164;MAPRE1B;CKAP5;HAUS2;CEP70

Cep63 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Cep63 itself. We selected most functions Cep63 had, and list some proteins which have the same functions with Cep63. You can find most of the proteins on our site.

Function	Related Protein
protein binding	FBXL8;MEA1;TXNRD2;SIN3B;NAPG;COL23A1;ANKRA2;MAP2K6;GPR37

Cep63 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cep63 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cep63.

DTNB; TBC1D15; SMARCE1; DISC1; TSHZ3

Alsara, M; Loffler, H; et al. Cep63 Recruits Cdk1 to the Centrosome-Letter. CANCER RESEARCH 75:777-778(2015).

Ma, LN; Quigley, I; et al. Multicilin drives centriole biogenesis via E2f proteins. GENES & DEVELOPMENT 28:1461-1471(2014).