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Cyp11b2

Official Full Name

cytochrome P450, family 11, subfamily b, polypeptide 2

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Rhesus Macaque

Source

E.coli
HEK293
Mammalian Cell
Yeast

Tag

His
His (Fc)
Avi
His|SUMO
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CYP11B2-194H	Recombinant Human CYP11B2	Mammalian Cell	His		Inquiry
Human	CYP11B2-1179H	Recombinant Human CYP11B2 Protein, His/SUMO-tagged	E.coli	His/SUMO		Inquiry
Human	CYP11B2-7129HCL	Recombinant Human CYP11B2 293 Cell Lysate	HEK293	N/A		Inquiry
Human	CYP11B2-2766H	Recombinant Human CYP11B2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Human	CYP11B2-2190H	Recombinant Human CYP11B2 Protein (25-503 aa), His-tagged	Yeast	His	25-503 aa	Inquiry
Human	CYP11B2-2766H-B	Recombinant Human CYP11B2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	CYP11B2-1134R	Recombinant Rhesus monkey CYP11B2 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	CYP11B2-959R-B	Recombinant Rhesus Macaque CYP11B2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	CYP11B2-959R	Recombinant Rhesus Macaque CYP11B2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Cyp11b2 Related Articles

Cyp11b2 involved in several pathways and played different roles in them. We selected most pathways Cyp11b2 participated on our site, such as ACE Inhibitor Pathway, Aldosterone synthesis and secretion, Biological oxidations, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cyp11b2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
ACE Inhibitor Pathway	CMA1;AGTR2;ATP6AP2;CYP11B2;AGT;CTSG;AGTR1;ACE
Aldosterone synthesis and secretion	PLCB3;CAMK2B;ADCY8;CREB3L3;CALM2;Adcy4;CAMK2D;MC2R;NR4A1
Biological oxidations	FDX1L;Sult2a2;CYP2K22;CYP2AD6;ABHD14B;CYP3A7-CYP3AP1;CYP24A1;CYP4F11;UGT1B4
Cytochrome P450 - arranged by substrate type	CYP1A1;CYP2J2;CYP4F22;CYP2R1;CYP7A1;CYP26A1;CYP4B1;CYP3A5;CYP2D6
Endogenous sterols	CYP1B1;CYP51A1;FDXR;CYP11B1;POMCB;FDX1L;CYP11A1;CYP46A1;FDX1
Glucocorticoid &amp	CYP17A1;CYP21A2;AKR1C21;CYP11B2
amp	CYP21A2;CYP11B2;AKR1C21;CYP17A1
Mineralcorticoid Metabolism	CYP17A1;CYP21A2;AKR1C21;CYP11B2
Glucocorticoid biosynthesis	CYP17A1;CYP21A2;CYP11B2;CYP11B1
Metabolic pathways	GLYCTK;LPCAT1;SLC33A1;PLA2G4F;PYCRL;DAO;RPN2;AMY2B;GNPDA1

Cyp11b2 has several biochemical functions, for example, corticosterone 18-monooxygenase activity, heme binding, iron ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Cyp11b2 itself. We selected most functions Cyp11b2 had, and list some proteins which have the same functions with Cyp11b2. You can find most of the proteins on our site.

Function	Related Protein
corticosterone 18-monooxygenase activity	CYP11B1;CYP11C1;CYP11B2
heme binding	CYP2K19;HBQ1;CYP46A1;GUCY1B3;IDO1;XGB;HRG-1;CYP2K16;JAK2
iron ion binding	P4HA1B;CYP21A2;BRSK2;CYP46A1.3;CYP2P8;FTH1;HBB;CYP46A1.1;HBAE3
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	NDOR1;MICAL2;CYP4F11;CYP2E1;POR;CYP11B2;CYP11C1;CYP4F18;CYP11A1
steroid 11-beta-monooxygenase activity	CYP11C1;CYP11B1;CYP11B2

Cyp11b2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cyp11b2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cyp11b2.

Kuppusamy, M; Caroccia, B; et al. A Novel KCNJ5-insT149 Somatic Mutation Close to, but Outside, the Selectivity Filter Causes Resistant Hypertension by Loss of Selectivity for Potassium. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 99:E1765-E1773(2014).

Nakamura, Y; Maekawa, T; et al. Adrenal CYP11B1/2 expression in primary aldosteronism: Immunohistochemical analysis using novel monoclonal antibodies. MOLECULAR AND CELLULAR ENDOCRINOLOGY 392:73-79(2014).