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DAK

  • Official Full Name

    dihydroxyacetone kinase 2 homolog (S. cerevisiae)

  • Overview

    This gene is a member of the family of dihydroxyacetone kinases, which have a protein structure distinct from other kinases. The product of this gene phosphorylates dihydroxyacetone, and also catalyzes the formation of riboflavin 4,5-phosphate (aka cyclin FMN) from FAD. Several alternatively spliced transcript variants have been identified, but the full-length nature of only one has been determined.
  • Synonyms

    DAK; dihydroxyacetone kinase 2 homolog (S. cerevisiae); dihydroxyacetone kinase 2 homolog (yeast); bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing); DKFZP586B1621; NET45; ATP dependent dihydroxyacetone kinase; Bifunctional ATP dependent dihydroxyacetone kinase/FAD AMP lyase (cyclizing); DHA kinase; Dha kinase/FMN cyclase; DHAK_HUMAN; Dihydroxyacetone kinase; Dihydroxyacetone kinase 2; FAD AMP lyase (cyclic FMN forming); FAD AMP lyase (cyclizing); FAD-AMP lyase (cyclic FMN forming); FAD-AMP lyase (cyclizing); FMN cyclase; Glycerone kinase; OTTHUMP00000235855; OTTHUMP00000235860; FAD-AMP lyase cyclizing; FAD-AMP lyase cyclic FMN forming; ATP-dependent dihydroxyacetone kinase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DAK-11819H Recombinant Human DAK, GST-tagged E.coli GST C-term-350a.a.
Human DAK-2112HCL Recombinant Human DAK cell lysate N/A
Mouse DAK-4299M Recombinant Mouse DAK Protein Mammalian Cell His
Mouse DAK-2196M-B Recombinant Mouse DAK Protein Pre-coupled Magnetic Beads HEK293
Mouse DAK-2196M Recombinant Mouse DAK Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat DAK-1771R Recombinant Rat DAK Protein Mammalian Cell His
Rat DAK-1429R Recombinant Rat DAK Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat DAK-1429R-B Recombinant Rat DAK Protein Pre-coupled Magnetic Beads HEK293
Zebrafish DAK-4520Z Recombinant Zebrafish DAK Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DAK Related Articles

DAK involved in several pathways and played different roles in them. We selected most pathways DAK participated on our site, such as Glycerolipid metabolism, Metabolic pathways, Carbon metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with DAK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycerolipid metabolismALDH2.2;AGPAT6;LIPC;PPAP2D;GPAT2;DGKA;DAK;ALDH9A1B;AGPAT9
Metabolic pathwaysINPP5B;FUT6;AGLA;CEL.1;ACSL4B;SHMT1;CHSY3;ackA;LIAS
Carbon metabolismPC;PCCB;RPIA;GPT2;SDS;RPE;PKLR;ADH5;GPIA
RIG-I-like receptor signaling pathwayIFNA10;DDX58;MAPK14A;ISG15;IFNPHI3;TBK1;MAPK13;IFIH1;IL8L1

DAK has several biochemical functions, for example, ATP binding, FAD-AMP lyase (cyclizing) activity, glycerone kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DAK itself. We selected most functions DAK had, and list some proteins which have the same functions with DAK. You can find most of the proteins on our site.

Function Related Protein
ATP bindingMYH11;FGFR3;PRKAA2;UBE2J2;CDC7;MAP2K3;FBXO18;MAPK7;TTLL5
FAD-AMP lyase (cyclizing) activity
glycerone kinase activity
metal ion bindingZNF266;B4GALT4;ZNF497;PLEKHF1;ZNF576.2;ZFP771;LMO7B;VAV3B;PRKCQ
protein bindingRITA1;DGCR8;ZNF543;PPP1R1A;MID1IP1;MEIS1;Casp3;TBC1D5;EPS15L1
triokinase activity

DAK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DAK here. Most of them are supplied by our site. Hope this information will be useful for your research of DAK.

SDCBP; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate

Reid, ME; Hipsky, CH; et al. The low-prevalence Rh antigen STEM (RH49) is encoded by two different RHCE*ce818T alleles that are often in cis to RHD*DOL. TRANSFUSION 53:539-544(2013).
Borrisholt, M; Nielsen, S; et al. Demonstration of CDX2 is Highly Antibody Dependant. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY 21:64-72(2013).
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