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DAP3

  • Official Full Name

    death associated protein 3

  • Overview

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q.
  • Synonyms

    DAP3; death associated protein 3; 28S ribosomal protein S29, mitochondrial; bMRP 10; DAP 3; DKFZp686G12159; MGC126058; MGC126059; mitochondrial 28S ribosomal protein S29; MRP S29; MRPS29; S29mt; death-associated protein 3; ionizing radiation resistance co;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DAP3-11824H Recombinant Human DAP3 protein(49-398 aa), GST-tagged E.coli N-GST 49-398 aa
Human DAP3-2333H Recombinant Human DAP3 Protein, GST-tagged Wheat Germ GST
Human DAP3-7077HCL Recombinant Human DAP3 293 Cell Lysate HEK293 N/A
Human DAP3-6475H Recombinant Human DAP3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DAP3-2454HF Recombinant Full Length Human DAP3 Protein, GST-tagged In Vitro Cell Free System GST 398 amino acids
Human DAP3-1309H Recombinant Human DAP3 Protein, His-tagged E.coli N-His Met1-Asn235
Mouse DAP3-4303M Recombinant Mouse DAP3 Protein Mammalian Cell His
Mouse Dap3-1310M Recombinant Mouse Dap3 Protein, His-tagged E.coli N-His Met1-Lys238
Mouse DAP3-2199M Recombinant Mouse DAP3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Dap3-2450M Recombinant Mouse Dap3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse DAP3-2199M-B Recombinant Mouse DAP3 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish DAP3-5701Z Recombinant Zebrafish DAP3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

DAP3 involved in several pathways and played different roles in them. We selected most pathways DAP3 participated on our site, such as Mitochondrial translation, Mitochondrial translation elongation, Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with DAP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Mitochondrial translationMRPS27;MRRF;CHCHD1;GFM1;MRPL49;MRPL3;MRPL42;MRPL51;GFM2
Mitochondrial translation elongationMRPS33;MRPS30;MRPL46;MRPL47;MRPS24;MRPL37;ICT1;MRPL49;MRPS28
Mitochondrial translation initiationMRPL49;MRPS35;MRPS36;MRPS28;MRPL3;MTFMT;MRPL38;GADD45GIP1;MRPS33
Mitochondrial translation terminationMRPL37;MRPL50;MRPS30;GADD45GIP1;MRPL45;MRPS31;ICT1;MTRF1L;MRPL44
Organelle biogenesis and maintenanceMRPL48;MARK4;FBF1;BBS4;PPRC1;GFM1;TRAF3IP1;KIF3CB;GFM2
TRAIL signaling pathway

DAP3 has several biochemical functions, for example, poly(A) RNA binding, protein binding, structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by DAP3 itself. We selected most functions DAP3 had, and list some proteins which have the same functions with DAP3. You can find most of the proteins on our site.

Function Related Protein
poly(A) RNA bindingTHOC4;NOC4L;HNRNPU;PURA;TNRC6B;SND1;DDX55;TNS1;EIF5
protein bindingRBPMS;DDX17;C22orf28;ACACB;EMILIN1;FBXW9;CDC23;ERCC3;POLR1D
structural constituent of ribosomeRPS19;MRPS30;RPL15;MRPL41;MRPS35;RPL5B;RPL11;MRPS22;MRPS9

DAP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DAP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DAP3.

NOA1; YBX1; C1qbp; ICT1; CNBP; NFKB2; IKBKG; MBNL1; ssrna_ug

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